Cephalexin

This page contains recent news articles, when available, and an overview of Cephalexin but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Cephalexin (when available)

Pharmacology and use:
Cephalexin is a first-generation cephalosporin antibiotic which is effective against most gram-positive bacteria. Cephalexin is used to treat otitis media and respiratory tract infections caused by susceptible staphylococci, Streptococcus pneumoniae, and group A beta-hemolytic streptococci. For the treatment of respiratory, skin, soft tissue, urintary tract infections caused by; S. pneumoniae, H. influenzae, staphylococci, S. pyogenes (group A ß-hemolytic streptococci), E. coli, P. mirabilis, Klebsiella sp, coagulase-negative staph

Mechanism Of Action:
Cephalexin, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that cephalexin interferes with an autolysin inhibitor.

News Articles on Cephalexin

Picture of the Month—Quiz Case  -  02 Jun 2008
In the week before evaluation, she had been started on a regimen of cephalexin; prednisolone, 15 mg/d with taper; and ibuprofen. Archives of Pediatrics

First Jack’s now Hugo’s last ride…  -  May 24, 2008
Hugo inherited half a bag of Hills Prescription ZD anti-allergy food, along with a hefty dose of Prednisone and Cephalexin pills. Over the years, Maggie and In-Forum,

Superbug bites dog  -  May 27, 2008
..."It's better to do a culture and then find out that it would have responded to cephalexin than not culture and let it go three weeks before realizing that San Francisco Chronicle,

MiddleBrook Pharmaceuticals Reports First Quarter 2008 Results  -  May 13, 2008
The Company currently markets the Keflex(R) brand of cephalexin and has received regulatory approval for MOXATAG(TM) -- the first and only once-daily Earthtimes (press release),

House of Israel leader says he didn’t know drugs were there  -  May 20, 2008
The drugs totaled nearly 10000 pills (9739) and included antibiotics such as cephalexin, erythromycin and amoxicillin, and a number of pain relievers and Jacksonville Daily Progress,

House of Israel: new arrest, new details  -  May 16, 2008
Officials say the six different types of prescription drugs, such as Lorazepam and Cephalexin, were in illegal possession. In addition, police confiscated KETK,

Examine the Indian Generics, 2008-2012: The Growing Threat to ...  -  May 12, 2008
Brand Names for Cephalexin, the Manufacturers and Price Comparisons Table 2.2 Sales Distributions (%) of Selected Indian Drug Manufacturers by Region, Earthtimes (press release),

Health ministry moves to stabilise rising drug prices  -  May 12, 2008
Ampicilin compact increased 14.38 per cent, Amoxicillin increased 11.84 per cent and Cephalexin increased 15.54 per cent in April. Viet Nam News,

Spike in Pen-G prices to hit bulk drug makers  -  Apr 3, 2008
These bulk drugs such as ampicillin, amoxicillin, cephalexin, and cloxacillin are used to make antibiotics formulations, which consumers use (finished Hindu Business Line,

Playful Pup Won't Stop Jumping Up  -  Apr 19, 2008
Cysts need to be treated with the antibiotic cephalexin, with ketoconazole or itraconazole if malassezia is present. Soak your dog's feet in warm water Glasgow Sunday Mail,

Surgical-Site Infection Following Breast Surgery: Time to Update ...  -  Apr 14, 2008
Dr. Throckmorton noted that, in 40% of her cases, the infection was not a Staph species, and cephalexin may have missed the mark. DG News

Cross-sectional prospective survey to study indication-based usage ...  -  Apr 14, 2008
...intramammary treatment, ampicillin combined with cloxacillin was most commonly used (n = 157; 36%), followed by cephalexin+streptomycin (n = 113; 26%). 7thSpace Interactive (press release),

Ways to Treat Skin Abscess  -  Apr 3, 2008
...antibiotics that kill staphylococci, such as dicloxacillin and cephalexin, may be used because of the high risk that the infection will spread to the Los Angeles Chronicle,

MiddleBrook Pharmaceuticals to Announce Fourth Quarter and Full ...  -  Feb 29, 2008
The Company currently markets the Keflex(R) brand of cephalexin and has received regulatory approval for MOXATAG(TM) -- the first and only once-daily CNNMoney.com (press release)

Nashville pharmacy offers free antibiotics  -  Feb 19, 2008
The drugs offered freely will be Ampicillin, Amoxicillin, PenicillinVK, Erythromycin, Cephalexin and Ciprofloxacin, all of which can be used in fighting Rocky Mount Telegram,

BeaconEquity.com - MiddleBrook Pharmaceuticals, Inc. (MBRK)  -  Mar 3, 2008
...and Keflex PULSYS product candidate, based on the antibiotic cephalexin, which is in Phase I clinical trials for skin and skin structure infections. TransWorldNews (press release),

Ward Drug Company of Nashville Launches Free Antibiotic Program  -  Feb 19, 2008
The antibiotics covered under this program include: Ampicillin, Amoxicillin, PenicillinVK, Erythromycin, Cephalexin and Ciprofloxacin. Carolina Newswire (press release),

More Challenges in the Prevention and Management of Community ...  -  Feb 18, 2008
Randomized, double-blind, placebo-controlled trial of cephalexin for treatment of uncomplicated skin abscesses in a population at risk for Annals of Internal Medicine

Pharma sees future in new drug delivery  -  06 Feb 2008
At present, the company's NDDS portfolio includes: Sporidex AF (Cephalexin), Cifran OD (Ciprofloxacin), Zanocin OD (Ofloxacin), and Flotral OD (Alfuzosin). Times of India,

Cephalexin: Drug Whys  -  Feb 4, 2008
Cephalexin is primarily used in susceptible skin and soft tissue infections, lower respiratory tract infections, bone (osteomyelitis) and joint infections, EMS1.com - Emergency Medical Service Resources,

Publix pharmacy offering to fill prescriptions for free  -  Feb 4, 2008
The grocery chain this week started offering seven oral antibiotics — Amoxicillin, Cephalexin, Sulfamethoxazole/Trimethoprim, Ciprofloxacin (excluding Spartanburg Herald Journal (subscription),

MiddleBrook Pharmaceuticals to Present at BIO CEO & Investor ...  -  Feb 5, 2008
The Company currently markets the Keflex(R) brand of cephalexin and has received regulatory approval for MOXATAG(TM) -- the first and only once-daily CNNMoney.com

Stockwire.com: CHAT LIVE with other shareholders about: (OTCBB ...  -  Jan 9, 2008
Cephalexin is the number-one most prescribed oral cephalosporin antibiotic and is also the number-one recommended oral antibiotic therapy for uncomplicated Trading Markets (press release),

BUYINS.NET: LPHI, MBRK, MKTAY, NURO, NVEC, VEXP Have Also Been ...  -  Feb 5, 2008
...and Keflex PULSYS product candidate, based on the antibiotic cephalexin, which is in Phase I clinical trials for skin and skin structure infections. Insurance News Net (press release),

Antibiotics free at Martin's  -  Jan 23, 2008
The drugs are amoxicillin; cephalexin; sulfamethoxazole/ trimethoprim (SMZ/TMP); ciprofloxacin; penicillin VK; ampicillin; doxycycline; and erythromycin South Bend Tribune,

How is strep throat detected by the doctor?  -  Feb 5, 2008
Ery-Tab, PCE, Pediazole, Ilosone)], azithromycin (Zithromax), and clarithromycin (Biaxin), and Cephalosporins [cephalexin (Keflex, Keftabs, Biocef )]. TamilStar.com,

Auriga and MiddleBrook to co-promote oral antiskin infection drug  -  Jan 8, 2008
Cephalexin, the generic form of Keflex, is said to be the number-one recommended oral antibiotic therapy for uncomplicated skin and skin structure Trading Markets (press release),

MiddleBrook Soars on FDA OK of Once-Daily Strep Antibiotic  -  Jan 24, 2008
MiddleBrook also is developing a once-daily formulation of the anti-infective cephalexin, he noted. The company currently markets Keflex, a cephalexin BioWorld Online,

MiddleBrook Pharmaceuticals Closes Private Placement of Common ...  -  Jan 30, 2008
The Company currently markets the Keflex(R) brand of cephalexin and has received regulatory approval for MOXATAG(TM) -- the first and only once-daily CNNMoney.com

Local drug manufacturers agree medicines law will bring prices down  -  Feb 2, 2008
Ochave said that Unilab’s top generic sellers include, Amoxicillin, Mefenamic Acid, Metformin, Cephalexin, and Ascorbic Acid, under this order. Manila Times,

MiddleBrook stock soars 139% over time-release antibiotic  -  Jan 25, 2008
MiddleBrook hopes to have a partner who can finance a pivotal test of timed-released Keflex, a version of another popular antibiotic, cephalexin. Baltimore Sun,

RealPennies.com: RealPennies.com: Turning Pennies into dollars ...  -  Jan 28, 2008
...and Keflex PULSYS product candidate, based on the antibiotic cephalexin, which is in Phase I clinical trials for skin and skin structure infections. Trading Markets (press release),

Moxatag approval a crucial first for MiddleBrook  -  Jan 28, 2008
One of these involved selling to a major shareholder, Deerfield Management, US rights to the first-generation cephalosporin antibiotic Keflex (cephalexin), In-PharmaTechnologist.com,

Sav-Rex offering free antibiotics  -  Jan 26, 2008
...the prescriptions most often filled for children, including amoxicillin, cephalexin, SMZ-TMP, ciprofloxacin, ampicillin, penicillin VK and erythromycin. The Mississippi Press - gulflive.com,

DSM Pharma Chemicals And DSM Anti-Infectives Awarded The Gold  -  Jan 24, 2008
DSM Anti-Infectives is the world’s leading supplier of active pharmaceutical ingredients such as amoxicillin, ampicillin, cephalexin and cefadroxil, BioResearch Online (press release),

Publix Pharmacies Fill Millionth Free Prescription, Add Drug  -  Jan 15, 2008
...amoxicillin -- cephalexin -- sulfamethoxazole/trimethoprim (SMZ-TMP) -- ciprofloxacin (excluding ciprofloxacin XR) -- penicillin VK -- ampicillin and StreetInsider.com (subscription),

More Challenges in the Prevention and Management of Community ...  -  Jan 17, 2008
Rajendran PM, Young D, Maurer T, Chambers H, Perdreau-Remington F, Ro P, et al. randomized, double-blind, placebo-controlled trial of cephalexin for Annals of Internal Medicine

middlebrook Pharmaceuticals Raises Up to $10 Million from ...  -  Nov 7, 2007
Pursuant to a sublicense of those intellectual property rights back to the Company, the Company will continue to operate its cephalexin PULSYS business. CNNMoney.com

Freedom to fix drug prices does not work, finds NPPA  -  Nov 14, 2007
The medicines that were scrutinised included commonly used drugs like Paracetamol, Diclofenec Sodium, Cephalexin and Ampicillin. “The annual price increase Business Standard,

Million get free Meijer drugs  -  Nov 6, 2007
They are Amoxicillin, Cephalexin, SMZ-TMP, Ciprofloxacin, Penicillin VK, Ampicillin and Erythromycin. Meijer's program allows customers, regardless of MLive.com,

Meijer's free antibiotics a big hit with customers  -  Nov 6, 2007
The program covers generic antibiotics most often prescribed for children: amoxicillin, cephalexin, SMZ-TMP, ciprofloxacin, penicillin VK, ampicillin and The Grand Rapids Press - MLive.com,

Southern Family Markets offering free antibiotics  -  Nov 6, 2007
The plan offers a 14-day supply of seven generic antibiotics prescriptions: amoxicillin, am-picillin, cephalexin, ciproflox-acin, erythromycin, The Decatur Daily,

Metro/State business briefs  -  Nov 5, 2007
The medicines include Amoxicillin, Cephalexin, SMZ-TMP, Ciprofloxacin, Penicillin VK, Ampicillin and Erythromycin. The health program is open to all DetNews.com,

Journal of the American Podiatric Medical Association  -  Nov 16, 2007
He was given a prescription for cephalexin, which he took for 1 week as directed and completed. He soaked his foot as directed in warm soapy water and Journal of the American Podiatric Medical Association (subscription)

�?页�?�调色版  -  Nov 14, 2007
...(cephalexin capsules, USP) is a first-generation cephalosporin antibiotic shown to be active against strains of both gram-positive and gram- negative 金�?界,

Business digest  -  Nov 7, 2007
...regardless of insurance or co-pay, can take a prescription to any Meijer pharmacy and get the designated antibiotic amoxicillin, cephalexin, SMZ-TMP, Cincinnati Enquirer,

City builder closes after bankruptcy  -  Nov 6, 2007
The prescriptions included in the free program are amoxicillin, cephalexin, SMZ-TMP, ciprofloxacin, Penicillin VK, ampicillin and erythromycin. Fort Wayne Journal Gazette,

Meijer Celebrates First Year of Free Prescriptions  -  Nov 5, 2007
They are: Amoxicillin, Cephalexin, SMZ-TMP, Ciprofloxacin, Penicillin VK, Ampicillin and Erythromycin. This no-strings-attached program means that any PR Newswire (press release),

Foss Co.'s eco-technology is health friendly  -  Nov 4, 2007
...resistant to certain antibiotics including methicillin and the more common antibiotics such as oxacillin, penicillin, cephalexin and amoxicillin. Portsmouth Herald News,

Piggly Wiggly pharmacies offer free generic antibiotics  -  Oct 6, 2007
The popular generic oral antibiotics included are: Amoxicillin, Ampicillin, Cephalexin, Ciprofloxacin (Excluding Ciprofloxacin XR), Erythromycin, Online Athens (subscription),

BERICHT: Buy Drugs Without Prescription. No Prior Prescription ...  -  Oct 7, 2007
...difference between celexa and prozac, cephalexin std, cephalexin indications, cephalexin antibiotic, complexes of cephalexin, chitosan, chitosan dietary Ermelo.org,

Buy Drugs Without Prescription. Safe and Secure Ordering.  -  Oct 3, 2007
...celexa crazy meds, cephalexin, cephalexin er, shelf life of cephalexin, how long is cephalexin good for, cephalexin antibiotic 500 x 500mg for dogs, LIVE-Wintersport.com,

Publix To Offer 7 Prescription Antibiotics For Free  -  Sep 27, 2007
The prescription antibiotics available under the program are amoxicillin, cephalexin, sulfamethoxazole/trimethoprim, ciprofloxacin, penicillin VK, Local6.com,

Doggone clever  -  Sep 15, 2007
That prompted a trip to the veterinarian and a prescription for 250 milligrams of Cephalexin twice a day. The last time Gypsy was given a prescription, Louisville Courier-Journal,

Wal-Mart Launches Phase Two of Prescription Program With New $4 ...  -  Sep 27, 2007
AMOXICILLIN 500MG QTY 30 AMOXIL 50MG/ML DROPS QTY 30ML* CEPHALEXIN 250MG QTY 28 CEPHALEXIN 500MG QTY 30 CIPROFLOXACIN 250MG QTY 14 CIPROFLOXACIN 500MG CNNMoney.com

Symptoms by treatment, Part 1  -  Sep 18, 2007
Antibiotics, such as cephalexin, clarithromycin, cefuroxime axetil, cefixime and a host of other generic names, may cause inflammation of the intestinal Sun.Star,

Brand Names/Synonyms:
Cephalexin is also known by the following brand names and/or synonymsAlcephin; Alexin; Alsporin; Biocef; CEX; Carnosporin; Cefa-Iskia; Cefablan; Cefadal; Cefadin; Cefadina; Cefaleksin; Cefalessina [Dcit]; Cefalexin; Cefalexin Sodium; Cefalexina [Inn-Spanish]; Cefalexine [Inn-French]; Cefalexinum [Inn-Latin]; Cefalin; Cefaloto; Cefaseptin; Cefax; Ceforal; Cefovit; Celexin; Cepastar; Cepexin; Cephacillin; Cephalexin; Cephalexin Hydrate; Cephalexin Monohydrate; Cephalexine; Cephalexinum; Cephanasten; Cephaxin; Cephin; Cepol; Ceporex; Ceporex Forte; Ceporexin; Ceporexin-E; Ceporexine; Check; Cophalexin; Durantel; Durantel Ds; Ed a-Ceph; Erocetin; Factagard; Felexin; Fexin; HSDB

Drug Category:
Cephalexin is categorized under the following by the FDA: Anti-bacterial Agents; Cephalosporins; ATC:J01DB01

Dosage Forms:
SUSPENSION; TABLET

Absorption:
It is rapidly absorbed after oral administration by the gastrointestinal tract

Interactions:
-->Interactions for Cephalexin:

Metformin ó In healthy subjects given single 500 mg doses of cephalexin and metformin, plasma metformin mean c_max and AUC increased by an average of 34% and 24%, respectively, and metformin mean renal clearance decreased by 14%. No information is available about the interaction of cephalexin and metformin following multiple doses of either drug.

Although not observed in this study, adverse effects could potentially arise from co-administration of cephalexin and metformin by inhibition of tubular secretion via organic cationic transporter systems. Accordingly, careful patient monitoring and dose adjustment of metformin is recommended in patients concomitantly taking cephalexin and metformin.

Probenecid ó As with other b -lactams, the renal excretion of cephalexin is inhibited by probenecid.

Drug / Laboratory Test Interactions

As a result of administration of Keflex, a false-positive reaction for glucose in the urine may occur. This has been observed with Benedictís and Fehlingís solutions and also with Clinitest® tablets.

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Chemical IUPAC Name:
8-(2-amino-2-phenyl-acetyl)amino-4-methyl-7-oxo-2-thia-6-azabicyclo[4.2.0]oct-4-ene-5-carboxylicacid

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