Cefuroxime

This page contains recent news articles, when available, and an overview of Cefuroxime but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Cefuroxime (when available)

Pharmacology and use:
Cefuroxime, a second-generation cephalosporin, is used to treat severe upper and lower respiratory tract infections, skin infections, otitis media, and surgical prophylaxis. For the treatment of the following infections (respiratory, skin, soft tissue, urinary tract infections, ear, nose, throat infectsion) caused by; S. pneumoniae, H. influenzae, staphylococci, S. pyogenes (group A ß-hemolytic streptococci), E. coli, P. mirabilis, Klebsiella sp, coagulase-negative staph. Also used to treat acute bacterial bronchitis in patients with COPD

Mechanism Of Action:
Cefuroxime, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that cefuroxime interferes with an autolysin inhibitor.

News Articles on Cefuroxime

Superbug battle goes on  -  ‎Aug 14, 2009‎
Three antibiotics - cefuroxime, cefalexin and ciprofloxacin - are no longer recommended for general use following an increase in C difficile cases, South Wales Argus

Treatments for Lyme Disease  -  ‎Aug 4, 2009‎
Alternative antibiotics can be cefotaxime and cefuroxime. There are dosing treatments with the antibiotics of two to three weeks of continuous treatment. Examiner.com

Streptococcus pneumoniae Serotype 3 among Costa Rican Children ...  -  ‎Aug 14, 2009‎
Strains were serotyped and antimicrobial susceptibility to penicillin, amoxicillin, cefuroxime, ceftriaxone, azithromycin and levofloxacin was determined by 7thSpace Interactive (press release)

[중국리�?�트] 주요 �?료�?�약품 수출입 현황-2  -  ‎Aug 9, 2009‎
Ceftriaxone, Cefuroxime, Ceftazidime과 같�?� preparation 수입량�?� �?�게 �?가했다. 2008년 Penicillin계 �?�약품 수출�?� 기본�?으로 2007년과 비슷한 추세를 보�?�며 디지틀보사

《国家基本�?�物目录》(2009版)  -  ‎Aug 18, 2009‎
9头孢呋辛Cefuroxime�?��?常释剂型�?注射剂(注释1：目录第9�?�“头孢呋辛�?包括头孢呋辛酯。) 33抗艾滋病用�?�(注释2：目录第33�?�“抗艾滋病用�?��?是指国家�?费治疗艾滋病的北方网

Buy cefuroxime. no prior perscription cefuroxime  -  ‎Jul 1, 2009‎
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Notable endophthalmitis study fails to alter US practice pattern  -  ‎Jun 25, 2009‎
In fact, the antibiotic that was used in the ESCRS study was cefuroxime, and that's almost never used here in the United States. OSN SuperSite

Simple and complex ways can help ophthalmologists avoid MRSA, MRSE ...  -  ‎Jun 25, 2009‎
I personally favor a fluoroquinolone for all three, but there is good evidence to support other choices, such as vancomycin and cefuroxime for intracameral OSN SuperSite

Preventing and Treating Lyme Disease  -  ‎Jun 28, 2009‎
Alternative treatments include cefuroxime and amoxicillin. Serious infections may require intravenous therapy, such as ceftriaxone. DentalPlans.com

第二代头孢�?�素  -  ‎Jul 9, 2009‎
...主�?代表�?�物为头孢呋辛(cefuroxime)�?头孢克洛（cefaclor）�?头孢孟多(cefamandole)�?头孢尼西（cefonicid）�?头孢雷特(ceforamide)。第二代头孢�?�素主�?用于治疗甲医盟网健康资讯

Orbus Announces Health Canada Approval of Cefuroxime Axetil for ...  -  ‎Apr 2, 2009‎
Cefuroxime Axetile is a broad spectrum antibiotic for the treatment of certain respiratory tract infections caused by bacteria, such as bronchitis; Filing Services Canada (press release)

Multiple routes of administration viable for endophthalmitis ...  -  ‎Apr 3, 2009‎
Reviewing the literature on this topic, Dr. Olson said that although intracameral cefuroxime is the only prophylactic regimen that has been demonstrated Modern Medicine

Orbus Pharma Inc. Reports 2008 Results  -  ‎Mar 31, 2009‎
Health Canada granted market authorization for the sale of Cefuroxime Axetil in Canada on March 4, 2009. A process variation to the file is being submitted FOXBusiness

التهاب الجيوب الأن�?ية.. أسبابه وعلاجه  -  ‎Apr 15, 2009‎
...acid أو أحد أدوية quinolone (مثل دواء levofloxacin)، أو أحد أدوية Macrolide (مثل دواء azithromycin)، أو أحد أدوية cephalosporin (مثل دواء cefuroxime). عرب نت 5

Tick trouble  -  ‎Mar 10, 2009‎
...who don't have allergies to this medication), and cefuroxime or erythromycin (for people who are allergic or cannot tolerate the first two antibiotics). Jackson Sun

A Prospective Cohort Study of One Hundred and Eighty-three Knees  -  ‎Mar 2, 2009‎
In our previous studies 26,27 , cefuroxime-impregnated cement was shown to be effective in the prevention of deep infection following primary total knee Journal of Bone and Joint Surgery (subscription)

What treatments work for bronchitis?  -  Jan 21, 2009
Cefuroxime axetil in the treatment of bronchitis: comparison with amoxicillin in a multicentre study in general practice patients. guardian.co.uk,

What treatments work for pneumonia?  -  Jan 21, 2009
Some of the most common antibiotics (and their brand names) are amoxicillin (Amoxil), erythromycin (Erymax, Erythrocin), cefuroxime (Zinacef, Zinnat), guardian.co.uk,

Treatment options for respiratory infections  -  Jan 27, 2009
...high-dose amoxicillin 1 g three times daily or amoxicillin-clavulanate 2 g twice daily or cefpodoxime 200 mg twice daily or cefuroxime 500 mg twice Clinical Advisor,

What treatments work for sinusitis?  -  Jan 21, 2009
Treatment of acute maxillary sinusitis in adults outpatients: comparison of a five versus ten day-course of cefuroxime axetil. guardian.co.uk,

What treatments work for mastitis?  -  Jan 21, 2009
Antibiotics that doctors use to treat mastitis include amoxicillin, cefalexin (brand names include Ceporex and Keflux), cefuroxime (Zinnat), guardian.co.uk,

What's the evidence for antibiotics?  -  Jan 21, 2009
A multicenter, randomized study comparing the efficacy and safety of intravenous and/or oral levofloxacin versus ceftriaxone and/or cefuroxime axetil in guardian.co.uk,

Orchid registers turnover of Rs 310cr for Q3FY09  -  Jan 29, 2009
During the quarter under review, Orchid received USFDA approvals for Cefuroxime Sodium Injections range in the Cephalosporin segment and for Divalproex Moneycontrol.com,

التهاب الجيوب الأن�?ية.. أسبابه وعلاجه  -  Jan 17, 2009
...acid أو أحد أدوية quinolone (مثل دواء levofloxacin)، أو أحد أدوية Macrolide (مثل دواء azithromycin)، أو أحد أدوية cephalosporin (مثل دواء cefuroxime). الشرق الاوسط,

طارق مصاروة عدم الثقة �?ـي تعاملنا مع مؤسساتنا وبلدنا!  -  Dec 1, 2008
وأمس اشتريت مضاداً حيوياً من نوع Cefuroxime 005 بتسعة دنانير ونص�? تقريباً، واذا بتقليدها الاردني يزيد عن سعر الاوروبية Glaxosmith Klein بدينار ونص�? الدينار الرأي,

Orchid receives USFDA nod for Cefuroxime  -  Oct 17, 2008
Chennai-based Orchid Chemicals & Pharmaceuticals (Orchid) has got approval for 3 of its Abbreviated New Drug Application (ANDA) for Cefuroxime drug by US Stock Watch,

Orchid gets USFDA approval for Cefuroxime  -  Oct 16, 2008
Cefuroxime an antibiotic resistant to most betalactamases and active against a wide range of gram-positive and gram -negative organisms is used in treating Myiris.com,

Antimicrobial Resistance Patterns Of Urinary Tract Pathogens And ...  -  Sep 28, 2008
80% of those E. coli in that year were also susceptible to gentamicin, 90% to cefuroxime and amikacin and 60% to piperacillin. By 2006 those similar strands Medical News Today (press release),

Market Live  -  Oct 16, 2008
12:10 pm: Orchid Chemicals & Pharmaceuticals has received approvals from USFDA for three of its abbreviated new drug application's for Cefuroxime injection Economic Times,

Modified depth, incisions for LASIK flap increase strength ...  -  Oct 9, 2008
Peter Barry, FRCS, spoke about intracameral cefuroxime and endophthalmitis. Intracameral cefuroxime may not only protect patients against endophthalmitis, OSN SuperSite (subscription),

Ranbaxy’s Achilles heel  -  Sep 25, 2008
The blacklisted drugs included antibiotic Cefuroxime Axetil and anti-bacterial Ciprofloxacin — drugs that helped fuel growth in the US — besides flagship Hindu Business Line,

Learn about the World Antibiotics Market  -  Sep 24, 2008
USP II-23Advancis's Keflex Receives FDA Approval II-23Wockhardt Gains Marketing Approval for Cefuroxime axetil inthe US II-23Wyeth's Mylotarq Receives International Business Times,

Learn about the World Antibiotics Market  -  Sep 24, 2008
USP II-23 Advancis's Keflex Receives FDA Approval II-23 Wockhardt Gains Marketing Approval for Cefuroxime axetil in the US II-23 Wyeth's Mylotarq Earthtimes (press release),

Thuốc giả và kém chất lượng: Vẫn khó quản lý  -  Sep 27, 2008
Theralene viên nén, Direxiode, Postinor, Dogmatil, Levitral, Quinin sunfat và một số thuốc dạng tiêm Acetaphen, Neotil, Cefuroxime, Paracétamol dạng ống An ninh thủ đô,

Cefuroxime may protect vision in addition to preventing ...  -  15 Sep 2008
BERLIN — Intracameral cefuroxime may not only protect patients against endophthalmitis, but may also protect final visual acuity in the case of infection, OSN SuperSite (subscription),

Tick trouble  -  15 Sep 2008
...who don't have allergies to this medication), and cefuroxime or erythromycin (for people who are allergic or cannot tolerate the first two antibiotics). MyFox Atlanta,

My experiences with the brown recluse  -  Sep 9, 2008
The doctor gave me a shot of the antibiotic Rocephin and prescribed an oral antibiotic, cefuroxime. These antibiotics worked for me, and I continued to put Carroll County News,

Prophylactic antibiotics for joint arthroplasty: Which one and for ...  -  Sep 5, 2008
Second-generation cephalosporins such as cefuroxime have also been used as prophylactic agents because of their broader coverage which includes activity Ortho SuperSite,

Antimicrobial Resistance Patterns of Urinary Tract Pathogens and ...  -  Sep 10, 2008
...to Co-trimoxazole (SXT), more than 80% to gentamicin (GN), more than 90% to cefuroxime (CXM) and amikacin (AN), and more than 60% to piperacillin (PIP). UroToday,

Orbus Pharma Inc.: Orbus Pharma Inc. Announces Additional Financing  -  Sep 8, 2008
...(v) the Corporations to pursue their interest in selling the Corporation's Cefuroxime Axetil business with net proceeds applied to reduce the related Trading Markets (press release),

Surgical Wound Mucormycosis Necessitating Hand Amputation  -  Sep 3, 2008
...distress syndrome and was treated with hydrocortisone (100 mg twice a day) for 2 weeks and intravenous cefuroxime (750 mg 3 times a day) for 10 days. RedOrbit,

�?ình chỉ hai loại thuốc không đạt chất lượng  -  Sep 8, 2008
S�?K: VD-1577-06 do cơ sở Công ty TNHH Dược phẩm NIC-PHARMA sản xuất và thuốc viên bao phim REETAC-500 (Cefuroxime Acetyl 500 mg), Lô SX: EHT06/B-02, Khanh Hoa,

Sagent Pharmaceuticals Launches Ceftriaxone, USP, and Cefuroxime ...  -  Jul 16, 2008
Cefuroxime for injection, USP, is a semisynthetic broad spectrum antibiotic agent for parenteral administration used to treat a variety of infections and is Earthtimes (press release),

Effectiveness and Safety of Short-Course Vs Long-Course Antibiotic ...  -  Aug 5, 2008
Short course therapy with cefuroxime axetil for group A streptococcal tonsillopharyngitis in children. Pediatr Infect Dis J. 1998;17(6):452-457. 25. RedOrbit,

Personal Health A Threat in a Grassy Stroll: Lyme Disease  -  Jul 15, 2008
Other options include cefuroxime axetil (Ceftin) and erythromycin. But these guidelines are controversial. They have been challenged by a nonprofit medical New York Times,

LIOs com antibiótico apresentam eficácia contra bactérias resistentes  -  Aug 4, 2008
No entanto, questões têm sido levantadas pelo uso “off-label�? de cefuroxime, ea resistência à droga pode aumentar com o tempo. Além disso, como o tempo de OSN SuperSite (subscription),

Q&A: DISEASE'S CAUSE, CURES  -  03 Jul 2008
Most people can be cured with a few weeks of oral antibiotics such as doxycycline, amoxicillin, or cefuroxime axetil. Those diagnosed with later stages of Newsday,

Intracameral cefuroxime is best option for endophthalmitis ...  -  Jun 30, 2008
Peter Barry, FRCS, made his case for why intracameral cefuroxime, and not topical fluoroquinolones, should be the standard of care for surgical prophylaxis OSN SuperSite (subscription),

Your physician knows best  -  Jun 5, 2008
I would like to cite an instant where my late mother who was 85 years old at the time, almost passed away, when a generic cefuroxime (bought from a SPC Daily Mirror,

Tick trouble  -  Jun 27, 2008
...who don't have allergies to this medication), and cefuroxime or erythromycin (for people who are allergic or cannot tolerate the first two antibiotics). MyFox WGHP,

Rosiglitazone may Slow Progression of Diabetic Retinopathy  -  Jun 26, 2008
Some of their products include Albenza (albendazole), Ceftin (cefuroxime axetil), Flonase (fluticasone proprionate), and Paxil (paroxetine hydrochloride). Medi News Direct,

Beware of Bug Bites and Stings  -  Jun 19, 2008
Antibiotics commonly used for oral treatment include doxycycline, amoxicillin, or cefuroxime axetil (Ceftin). People with certain illnesses related to the Food Consumer,

Is DRA responsible for cheap ineffective brand drugs?  -  Jun 16, 2008
SPC amoxicillin cefuroxime or will they prescribe a more effective amoxicillin such as amoxil or oral Zinnat or Zinacef IV or any other effective brand? Daily Mirror,

When Are Antibiotics For Lyme Disease Medically Necessary?  -  Jun 7, 2008
Most doctors prescribe doxycycline, (for adults and children over eight years old) or amoxicillin or cefuroxime (for adults and children under eight). eMaxHealth.com,

Orchid Chemicals gains on strong FY 2008 numbers  -  May 29, 2008
...received approval from the US Food & Drug Administration (US FDA) for its abbreviated new drug application for cefuroxime axetil tablets. NDTV.com,

Sheriff ramps up prescription drug battle  -  May 31, 2008
Cefuroxime axetil is an antibiotic. Pravastatin is a cholesterol medication. Diclofenac sodium is an anti-inflammatory drug. Cymbalta treats depression. Princeton Times Leader,

Summer Safety  -  May 12, 2008
...who don't have allergies to this medication), and cefuroxime or erythromycin (for people who are allergic or cannot tolerate the first two antibiotics). FOX 11 Online,

Aurobindo Pharma receives nine product approval from MCC - South ...  -  May 12, 2008
Product Name : Zinoxime Active ingredient : Cefuroxime Axetil Dosage Form : Tablet Strength: 125mg, 250mg,500mg Category : Anti-infective 5. Equity Bulls,

Orbus Pharma Inc. Reports First Quarter 2008 Results  -  May 6, 2008
...with Nobelpharma to market Metoprolol Succinate XR in Turkey and through an agent, Helm Portugal, to market Cefuroxime to another licensee in Portugal. Filing Services Canada (press release),

Antibiotic-soaked IOLs show efficacy against bacteria  -  May 6, 2008
However, issues have been raised by the off-label use of cefuroxime, and resistance to the drug may increase over time. In addition, because the average OSN SuperSite (subscription),

Brand Names/Synonyms:
Cefuroxime is also known by the following brand names and/or synonymsAncef; Biofuroksym; Ceclor; Ceclor Cd; Cedax; Cefditoren; Cefizox; Cefotan; Ceftin; Ceftizoxime Sodium; Cefurax; Cefuril; Cefuroxim; Cefuroxime; Cefuroxime Axetil; Cefuroxime Free Acid; Cefuroxime Sodium; Cefuroxime Sodium Salt; Cefuroxime [Usan:Ban:Inn]; Cefuroxime and Dextrose in Duplex Container; Cefuroximo [Inn-Spanish]; Cefuroximum [Inn-Latin]; Cefzil; Cephuroxime; Ceptaz; Duricef; Elobact; Fortaz; Keflex; Keftab; Kefurox; Kefurox in Plastic Container; Kerurox; Mandol; Maxipime; Mefoxin; Monocid; Omnicef; Oraxim; Rocephin; Sharox; Tazicef; Vantin; Velosef; Zinacef; Zinacef Danmark; Zinacef in Plastic Container; Zinat; Zinnat

Drug Category:
Cefuroxime is categorized under the following by the FDA: Anti-bacterial Agents; Cephalosporins; ATC:J01DC02

Dosage Forms:
POWDER; POWDER FOR SOLUTION; TABLET

Absorption:
Well absorbed from the GI tract (bioavailability is 37-52%)

Interactions:
-->Interactions for Cefuroxime:

Drug/Laboratory Test Interactions: A false-positive reaction for glucose in the urine may occur with copper reduction tests (Benedictís or Fehlingís solution or with ClinitestÒ tablets) but not with enzyme-based tests for glycosuria. As a false-negative result may occur in the ferricyanide test, it is recommended that either the glucose oxidase or hexokinase method be used to determine blood plasma glucose levels in patients receiving cefuroxime.

Cefuroxime does not interfere with the assay of serum and urine creatinine by the alkaline picrate method.

Chemical IUPAC Name:
4-(carbamoyloxymethyl)-8-[2-(2-furyl)-2-methoxyimino-acetyl]amino-7-oxo-2-thia-6-azabicyclo[4.2.0]oct-4-ene-5-carboxylic acid

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