CPT-11

This page contains recent news articles, when available, and an overview of CPT-11 but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

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Bevacizumab Plus Irinotecan Has Significant Activity in Treatment ...  -  Jun 5, 2008
However, each of these adverse events was seen more frequently in the group receiving dual bevacizumab/CPT-11 compared with the arm receiving bevacizumab DG News

Cancer of the Esophagus and Stomach  -  Jun 14, 2008
CPT-11 plus cisplatin in patients with advanced, untreated gastric or gastroesophageal junction carcinoma: results of a phase II study. Cancer. RedOrbit,

Study Suggests Survival Benefit from Radioactive Microsphere ...  -  02 Jun 2008
...patients (pts) with metastatic colorectal cancer (mCRC) after the failure of fluoropyrimidine, irinotecan (CPT-11), and oxaliplatin (OHP) chemotherapy. Business Wire (press release),

Ted Kennedy’s Recent Diagnosis of Glioblastoma Raises Awareness of ...  -  May 20, 2008
Salvage chemotherapy with CPT-11 for recurrent oligodendrogliomas. Journal of Neuro-oncology. 2002;59(2):157-63. 38. Lawson HC, Sampath P, Bohan E, et al. Cancer Consultants,

Chat transcript: Dr. Andrew Norden answers questions about brain ...  -  May 21, 2008
...sensis__Guest_: Are there any other promising treatments on the horizon other than Temodar, CPT-11/Avastin right now? Dr__Andrew_Norden: There is a very Boston Globe,

Seeing cancer struggle as a mountain to climb  -  May 25, 2008
His youth and good medical history made him an ideal candidate for two experimental drugs, Avastin and CPT-11, prescribed after a two-day consultation in Philadelphia Inquirer,

Enzon Announces Clinical Data from PEG-SN38 and rhMBL Studies at ASCO  -  May 20, 2008
US Although unmodified SN38 is up to 1000 times more potent than CPT-11, it has not been converted into a viable drug candidate because it is insoluble. PharmaLive.com (press release),

Recurrent Brain Cancer Responds To New Treatment  -  Feb 29, 2008
The researchers set out to determine the clinical benefit of BV, both alone and in combination with CPT-11, in a multicenter, randomized phase II trial. Science Daily (press release)

Enzon's cancer drug found effective against tumors  -  Dec 11, 2007
EZN-2208 treatment cured animals and outperformed CPT-11, in very aggressive and advance disease preclinical models. SN38 is the active metabolite of the Pharmaceutical Business Review

Comment: Texans take a stand for research funding  -  Nov 24, 2007
Examples include FOLFOX, a chemotherapy for colorectal cancer; CPT-11, a chemotherapy for colorectal and other malignancies; Gemcitabine, a chemotherapy for San Antonio Express,

Enzon Provides New Data on Customized Linker Technology  -  Oct 30, 2007
SN38 is the active metabolite of the widely used cancer drug CPT-11, marketed as Camptosar® in the US Although unmodified SN38 is 1000 times more potent Business Wire (press release),

Data Reinforce The Value Of UFT As An Important Treatment Option ...  -  Sep 27, 2007
SCOUT: Study of CPT-11 with Oxaliplatin combined with UFT plus leucovorin Therapy b. CETUFTIRI: Combination of CETuximab, UFT, leucovorin and IRInotecan c. Medical News Today (press release),

SCOUT Regimen Useful as First-Line Treatment for Metastatic ...  -  Sep 26, 2007
...[Presentation title: Study of CPT-11, Oxaliplatin, UFT Triple Therapy (SCOUT) in Metastatic Colorectal Cancer: An effective and Well Tolerated Regimen. DG News

Cell Therapeutics, Inc. (CTI) Announces Agreement to Acquire SMi ...  -  Jul 24, 2007
CNNMoney.com...new anticancer agents and was deeply involved in the development of mitoxantrone, fludarabine, paclitaxel, docetaxel, gemcitabine, CPT-11, and others.

Anticancer nanodelivery vehicles  -  Jun 7, 2007
In-PharmaTechnologist.com,These include GlaxoSmithKline's Hycamtin (topotecan) and Pfizer's Camptostar (irinotecan) which is also known as CPT-11.

Pro-Pharmaceuticals Submits Data to Begin a 505 (b)(2) Filing with ...  -  Jun 11, 2007
PharmaLive.com (press release),Irinotecan is also known as CPT-11. According to market analysts, the worldwide market for Irinotecan is more than $1 billion. The proposed mechanism of

Accelerate Brain Cancer Cure Funds Record Number of Research Programs  -  May 15, 2007
PR Newswire (press release),In addition, clinical trials for promising therapeutic regimens, such as the combination of Avastin and CPT-11, offer new hope for patients."

Genetically modified cells attack tumors  -  Dec 24, 2006
Hindu,Moreover, since the drug, called CPT-11 (irinotecan), is already used to treat cancers, doctors and scientists already know how the drug behaves in humans.

Anti-Cancer 'Smart Bomb' Homes in on Deadly Tumors  -  Dec 21, 2006
Haber Sağlık,..."CPT-11 is the drug that's used to treat kids today," Aboody said. "It goes throughout the body and only a very small percent of it reaches the tumors."

Drug, stem cells treat neuroblastoma  -  Dec 22, 2006
United Press InternationalThree days later the team injected the mice with CPT-11 (irinotecan), a human chemotherapy drug. The CPT-11 went to all parts of the animals' bodies,

Neural cells aid in healing tumors  -  Dec 23, 2006
Whittier Daily News,The stem cells carried the gene for a rabbit protein that made the chemotherapy drug CPT-11 a thousand times more potent, Aboody said.

Genetically Modified Cells Attack Tumors  -  Dec 29, 2006
HappyNews.com,The cells produced an enzyme that activated the chemotherapy drug CPT-11 (irinotecan) at the site of the tumors. A report on this work appears in the Dec.

TAIWAN PHARMACEUTICAL FIRM WINS US PATENT FOR SN-38 PRODUCTION  -  Dec 22, 2006
Therapeutics Daily (subscription) (press release),SN-38, the active metabolite of irinotecan (CPT-11), is widely used by many new drug companies to develop new camptothecin derivatives.

US Patent Granted to ScinoPharm for the Production of SN-38  -  Dec 21, 2006
ag-IP-news Agency,According to a press release by the company, the irinotecan (CPT-11) is widely used by many drug companies to develop new camptothecin derivatives.

Genetically modified cells attack tumors  -  Dec 24, 2006
Hindu,Moreover, since the drug, called CPT-11 (irinotecan), is already used to treat cancers, doctors and scientists already know how the drug behaves in humans.

Genetically modified cells attack tumors  -  Dec 23, 2006
HULIQ,Moreover, since the drug, called CPT-11 (irinotecan), is already used to treat cancers, doctors and scientists already know how the drug behaves in humans.

Anti-Cancer 'Smart Bomb' Homes in on Deadly Tumors  -  Dec 21, 2006
Haber Sağlık,..."CPT-11 is the drug that's used to treat kids today," Aboody said. "It goes throughout the body and only a very small percent of it reaches the tumors."

Drug, stem cells treat neuroblastoma  -  Dec 22, 2006
United Press InternationalThree days later the team injected the mice with CPT-11 (irinotecan), a human chemotherapy drug. The CPT-11 went to all parts of the animals' bodies,

Neural cells aid in healing tumors  -  Dec 23, 2006
Whittier Daily News,The stem cells carried the gene for a rabbit protein that made the chemotherapy drug CPT-11 a thousand times more potent, Aboody said.

Genetically Modified Cells Attack Tumors  -  Dec 23, 2006
Medical News Today (press release),The cells produced an enzyme that activated the chemotherapy drug CPT-11 (irinotecan) at the site of the tumors. A report on this work appears in the Dec.

TAIWAN PHARMACEUTICAL FIRM WINS US PATENT FOR SN-38 PRODUCTION  -  Dec 22, 2006
Therapeutics Daily (subscription) (press release),SN-38, the active metabolite of irinotecan (CPT-11), is widely used by many new drug companies to develop new camptothecin derivatives.

US Patent Granted to ScinoPharm for the Production of SN-38  -  Dec 21, 2006
ag-IP-news Agency,According to a press release by the company, the irinotecan (CPT-11) is widely used by many drug companies to develop new camptothecin derivatives.

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