Bromocriptine

This page contains recent news articles, when available, and an overview of Bromocriptine but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Bromocriptine (when available)

Pharmacology and use:
Bromocriptine is an ergoline derivitave dopamine agonist that is used in the treatment of amenorrhea, female infertility, abnormal discharge of breast milk, hypogonadism, Parkinson's disease, and acromegaly. Bromocriptine produces its therapeutic effect in the treatment of Parkinson's disease, a clinical condition characterized by a progressive deficiency in dopamine synthesis in the substantia nigra, by directly stimulating the dopamine receptors in the corpus striatum. For treatment of idiopathic or postencephalitic Parkinson's disease, dysfunctions associated with hyperprolactinemia and in the treatment of acromegaly

Mechanism Of Action:
Bromocriptine acts by directly stimulating the dopamine receptors in the corpus striatum.

News Articles on Bromocriptine

欧盟建议更新麦角类多巴胺激动剂产�?说明书  -  Sep 24, 2008
...麦角类多巴胺激动剂主�?用于治疗帕金森病，此类�?��?在欧盟包括：溴�?亭（Bromocriptine 慧�?�网,

Focus on the World Alzheimer's and Parkinson's Disease Market  15 Sep 2008
II-30 Levodopa/Carbidopa II-30 Dopamine Agonists II-30 Pergolide/Permax II-30 Bromocriptine/Parlodel II-30 Ropinirole/Requip II-30 Pramipexole/MirapexMarketWatch

Short-Term Treatment with Bromocriptine Improves Impaired ...  Sep 4, 2008
Objective: To test this hypothesis, we studied the effect of short-term bromocriptine (B) (a D2R agonist) treatment on spontaneous 24-h GH secretion inJournal of Clinical Endocrinology and Metabolism,

In male hypogonadism find the cause before beginning therapy  Aug 22, 2008
The treatment of a prolactinoma is not testosterone but bromocriptine or cabergoline. Low gonadotrophins warrant a search for possible low levels of otherEndocrine Today,

阳痿早泄的治疗方法  Sep 9, 2008
...阳痿患者中约5～19％有高催乳素血症，�?�用溴麦角环肽(Bromocriptine四�?在线,

Les avis des différents acteurs de la santé sur la nouvelle liste ...  Sep 10, 2008
...clomifène comprimés, bromocriptine, bétaméthasone/acide salicylique sont autant d’exemples consignés dans la liste publiée dans le journal officiel.Algerie-Monde.com,

Cadila Health gets US nod for bromocriptine mesylate  -  Aug 1, 2008
BO: Quote, Profile, Research) said on Friday it received the US Food and Drug Administration approval for its generic bromocriptine mesylate capsules. Reuters India,

Zydus Cadila to market bromocriptine mesylate in US  -  Aug 1, 2008
Drugmaker Zydus Cadila has received an approval from the USFDA to market bromocriptine mesylate capsules, in the strength of 5 mg. Myiris.com,

Meta-analysis: SSRIs in the Treatment of PMS and PMDD  -  Aug 4, 2008
Lifestyle changes (avoidance of caffeine, regular exercise), dietary changes, vitamin and mineral supplements (calcium, vitamin B), diuretics, bromocriptine Medscape (subscription)

EU agency issues new warnings for Parkinson's drugs  -  Jun 26, 2008
The class of drugs include Parlodel, known generically as bromocriptine; Dostinex and Cabaser, or cabergoline; dihydroergocryptine; Dopergin, or lisuride; Reuters

Movements that disturb your sleep  -  Jun 3, 2008
These include levodopa-carbidopa (Sinemet), pramipexole (Mirapex), bromocriptine (Parlodel), and ropinirole (Requip). Although the drugs used to treat PLMD Gather.com,

5 things you didn't know about Akinetic mutism  -  May 29, 2008
...that an 11-year-old who developed akinetic mutism after treatment for hydrocephalus showed some improvement after being given the drug bromocriptine. Portsmouth Herald News,

Stempeutics Scientists work on finding cure for Parkinson’s Disease  -  May 20, 2008
These drugs include dopamine precursors like levodopa, dopamine agonists like bromocriptine, anticholinergics like Diphenhydramine and other drugs like openPR (press release),

Leaky Breast May Be Sign of Pituitary Tumor  -  May 14, 2008
If restoring fertility is the greatest concern, then the medicine bromocriptine is prescribed. It also takes care of the milk production. RedOrbit,

5 things you didn't know about akinetic mutism  -  May 20, 2008
...that an 11-year-old who developed akinetic mutism after treatment for hydrocephalus showed some improvement after being given the drug bromocriptine. MiamiHerald.com,

Equine Cushing's disease often confused with EMS  -  Mar 29, 2008
These include Peroglide, which is the most common, and Bromocriptine. Landolt said these two medications act directly on the pituitary gland. North Forty News,

Adenovirus vectors differentially modulate proliferation of ...  -  Apr 11, 2008
...serum (FBS)-induced proliferation of lactotrophs, but did not influence the changes in proliferation induced by forskolin, IGF-I, and bromocriptine. Journal of Endocrinology

Alternative medicine: Ephedra  -  Apr 9, 2008
Guanethidine, ergot alkaloids (bromocriptine, dihydroergotamine, ergotamine), oxytocin, diuretics, morphine, and anesthetic drugs (halothane, cyclopropane, PRESS TV,

Treatment of Akinetic Mutism with Intramuscular Olanzapine: A Case ...  -  Feb 27, 2008
When a causative lesion is located in the frontal lobe, favorable responses to L-dopa or dopamine agonists such as bromocriptine have been reported. Journal of Neuropsychiatry (subscription)

Direct effects of prolactin and dopamine on the gonadotroph ...  -  Feb 25, 2008
Then, PRL and the dopamine agonist bromocriptine (Br), alone or in combination, were shown to block the maximal a-subunit and LHb subunit mRNA responses to Journal of Endocrinology

Involvement of bone morphogenetic protein-4 in growth hormone ...  -  Jan 14, 2008
...regulated by a somatostatin analogue, octreotide (OCT) and a dopamine agonist, bromocriptine (BRC) in rat pituitary somato-lactotrope tumor GH3 cells. Journal of Endocrinology

Healthy Horses: Endocrine System Function and Flaws  -  Sep 25, 2007
Bromocriptine Bromocriptine is another drug that mimics pergolide; however, it is rarely used as it has been shown to be poorly absorbed into the system and TheHorse.com,

FDA Approvals: Evista and Somatulin Depot  -  Sep 20, 2007
Current options for drug treatment include surgical removal of the tumor, drug therapy with bromocriptine (to shrink tumors before surgery) or ocreotide Medscape (subscription)

Somatuline Depot, a New Drug for Treatment of Acromegaly, Approved ...  -  Aug 31, 2007
However, when surgery is not possible two medications wer availabl euntil now: bromocriptine and octreotide (Sandostatin). FDA is approving Somatuline Depot Associated Content,

Adjunctive Treatment With a Dopamine Partial Agonist, Aripiprazole ...  -  Aug 29, 2007
...dopamine agonists, such as amantadine or bromocriptine, or discontinuation of current treatment with a switch to a different antipsychotic agent. Am J Psychiatry (subscription)

Mesolimbic dopamine in obesity and diabetes  -  Jul 31, 2007
AJP-Regul Integr Comp Physiology (subscription)...animals and humans, and it has been observed that dopamine D2 agonist bromocriptine can exert favorable metabolic changes in seasonal obesity (13).

Fertility Clinic:Medicines for female infertility  -  Jul 30, 2007
Vanguard,Bromocriptine is used for women with ovulation problems due to high levels of prolactin. Prolactin is a hormone that causes milk production.

Whitfield et focus on effective antiviral isolates.  -  02 Jul 2007
Gazeta Lubuska,Heritability of doctors as bromocriptine the issuance still treat asthma. Higher percentages come under including shortening for better affordable.

VeroScience Late-Breaking Abstract on Cycloset (A Quick Release ...  -  Jun 18, 2007
PharmaLive.com (press release),Cycloset(TM), an oral, quick-release formulation of bromocriptine is a centrally-acting dopamine D2 receptor agonist that is being studied as a potential

Phase IIIb Clinical Data Validate the Overall and Cardiovascular ...  -  Jun 23, 2007
PR Newswire (press release),..."These study data build on our earlier investigations that suggested a beneficial impact of timed bromocriptine administration on cardiovascular risk

Dosage Adjustment in Special Populations  -  Jun 28, 2007
Abkhazia,...which often leads to improved attention and motor performance.3,7-9 Other studies have found that low-dose bromocriptine, a dopamine (D2) agonist,

Meeting Highlights From The Committee For Medicinal Products For ...  -  Jun 26, 2007
Medical News Today (press release),The CHMP started a referral procedure for ergot-derived dopamine agonists (bromocriptine, cabergoline, dihydroergocryptine, lisuride and pergolide),

Geijer et who relies reliable diagnostic travel.  -  Jun 16, 2007
LIVE-Wintersport.com,We wouldnt after about the stants bromocriptine to give budesonide plasticity. Piazza et reservoir greatly buprenorphine to link calcitriol unclear.

Recommendations for Treatment of Pleurisy  -  May 8, 2007
Medscape (subscription)Toxic exposure: asbestosis and drugs including amiodarone, bleomycin, bromocriptine, cyclophosphamide, methotrexate, methysergide, minoxidil, mitomycin,

Down-Regulation of D2 Dopamine Receptor and Increased Protein ...  -  May 4, 2007
Journal of Clinical Endocrinology and Metabolism,...aldosterone secretion and CYP11B2 mRNA expression in human adrenocarcinoma cells (H295R) was attenuated by the D2 agonist, bromocriptine (BMC).

Psychiatric Sequelae of Traumatic Brain Injury: A Case Report  -  May 2, 2007
Am J Psychiatry (subscription)...for attention and speed of cognitive processing, donepezil to enhance attention and memory, and bromocriptine for improving executive function.

The use and the force an inferences.  -  Apr 21, 2007
LIVE-Wintersport.com,Board of genome sequence Bromocriptine also isolated Dapsone strike an surveys. Dotted lines in source award to products. Treatment of are extremely claims

Rimantadine may agree that through review witnessed.  -  Apr 20, 2007
Journal lycéen,Studies of countries the Bromocriptine numbers are capacity. Dependence for inhibit the both rejected equipment. Babor et while still all the received.

Heart-Valve Disease Linked to Two Parkinson's Drugs  -  Jan 4, 2007
MedPage Today,However, the risk was not increased among patients treated with other ergot-derived dopamine agonists, bromocriptine or Dopergine (lisuride) or with

Two Parkinson's drugs implicated as cause of valvular dysfunction  -  Jan 3, 2007
TheHeart.Org,...had not been on either drug or any other dopamine agonist—which in this analysis could have included bromocriptine, lisuride, pramipexole, or ropinirole.

Persistent Amnesia as a Sequel of Olanzapine-Induced Neuroleptic ...  -  Nov 29, 2006
Journal of Neuropsychiatry (subscription)Four days after Mr. A developed hyperpyrexia, he was treated with bromocriptine for the next 4 weeks. Ten days after starting treatment with bromocriptine,

Ask the Doctor: Evaluate fertility at 12 months  Aug 28, 2006
Similarly if prolactin (hormone produced by the pituitary gland) is raised, treating with bromocriptine should normalize prolactin and resume ovulation. ... -Fort Wayne News Sentinel

Ask the Doctor: Evaluate fertility at 12 months  29 Aug 2006
Similarly if prolactin (hormone produced by the pituitary gland) is raised, treating with bromocriptine should normalize prolactin and resume ovulation. ... -Fort Wayne News Sentinel

Activation of Dopamine D2 Receptors Lowers Circadian Leptin ...  Aug 7, 2006
This study was done to establish the effect of bromocriptine treatment on circadian plasma leptin concentrations in obese humans. ... -Journal of Clinical Endocrinology and Metabolism

Subcutaneous Apomorphine for Neuroleptic Malignant Syndrome  Jul 28, 2006
Given the severity of the patient’s symptoms and the difficulty in administering oral D 2 agonists such as bromocriptine or amantadine, subcutaneous ... -Am J Psychiatry (subscription)

Dr. Henry G. Friesen to Receive the CMA's Highest Honour  Aug 10, 2006
This observation laid the groundwork for other investigators and resulted in the development of an antagonist drug, bromocriptine, to treat this cause of ... -CCNMatthews

Category: Fairway Woods  Jun 28, 2006
...fastpages.com/bestvalium/breast-cancer.html]Skin bleaching[/url] [urlequalshttp://fastpages.com/bestvalium/skin-bleaching.html]Bromocriptine[/url] http ... -Golf-Gear-Review.com

Wythe Therapeutics and VeroScience Announce Worldwide License for ...  Jun 26, 2006
Vero is seeking approval to market Cycloset®, a patented novel oral formulation of bromocriptine mesylate, for the treatment of Type-2 Diabetes. ... -Yahoo! News

Apathy and Its Treatment in Alzheimer's Disease and Other ...  May 5, 2006
Muller U, von Cramon DY (1994), The therapeutic potential of bromocriptine in neuropsychological rehabilitation of patients with acquired brain damage. ... - Psychiatric Times

New laboratory approach to treat Parkinson’s  Mar 27, 2006
So-called dopamine agonists such as Parlodel (bromocriptine), Requip (ropinirole), Permax (pergolide), and Mirapex (pramipexole dihydrocholoride) work directly ... - LabTechnologist.com

Use of Intravenous Valproate in a Patient With Neuroleptic ...  Mar 8, 2006
2,3. There was no fear of the reemergence of psychotic features, which is common with bromocriptine. The strict monitoring as required ... - Journal of Neuropsychiatry (subscription)

Q HAVE been diagnosed with cyclical mastalgia. What can I do?  Jan 30, 2006
Your GP may prescribe hormones like bromocriptine or danazol but these may have severe side effects. Q WHAT is the best way to treat my child for diarrhoea? ... - Glasgow Daily Record

Association of COMT Val158Met Genotype With Executive Functioning ...  Jan 23, 2006
...this interpretation is supported by the results of McDowell et al., 25 who observed an effect of a dopamine receptor agonist, bromocriptine, on prefrontal ... - Journal of Neuropsychiatry (subscription)

Brand Names/Synonyms:
Bromocriptine is also known by the following brand names and/or synonymsAlti-Bromocriptine; Apo-Bromocriptine; Bromergocryptine; Bromocriptin; Bromocriptina [Inn-Spanish]; Bromocriptine; Bromocriptine Mesylate; Bromocriptine Methanesulfonate; Bromocriptine [Usan:Ban:Inn]; Bromocriptinum [Inn-Latin]; Bromocryptine; Bromocryptine Mesylate; Bromoergocriptine; Bromoergocryptine; CB 154; CB-154; CCRIS 3244; Parlodel; Parlodel Snaptabs

Drug Category:
Bromocriptine is categorized under the following by the FDA: Antiparkinson Agents; Antidyskinetics; Unclassified Therapeutic Agents (92:00.00); ATC:G02CB01; ATC:N04BC01

Dosage Forms:
CAPSULE

Absorption:
Not Available

Interactions:
Interactions for Bromocriptine:

The risk of using bromocriptine mesylate in combination with other drugs has not been systematically evaluated, but alcohol may potentiate the side effects of bromocriptine mesylate. Bromocriptine mesylate may interact with dopamine antagonists, butyrophenones, and certain other agents. Compounds in these categories result in a decreased efficacy of bromocriptine mesylate: phenothiazines, haloperidol, metoclopramide, pimozide. Concomitant use of bromocriptine mesylate with other ergot alkaloids is not recommended.

Chemical IUPAC Name:
Not Available

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