Betamethasone Dipropionate

This page contains recent news articles, when available, and an overview of Betamethasone Dipropionate but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Betamethasone Dipropionate
(when available)

Pharmacology and use:
Betamethasone and its derivatives, betamethasone sodium phosphate and betamethasone acetate, are synthetic glucocorticoids. Used for its antiinflammatory or immunosuppressive properties, betamethasone is combined with a mineralocorticoid to manage adrenal insufficiency and is used in the form of betamethasone benzoate, betamethasone dipropionate, or betamethasone valerate for the treatment of inflammation due to corticosteroid-responsive dermatoses. Betamethasone and clotrimazole are used together to treat cutaneous tinea infections. For relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses

Mechanism Of Action:
Betamethasone is a glucocorticoid Receptor Agonist. The antiinflammatory actions of corticosteroids are thought to involve lipocortins, phospholipase A2 inhibitory proteins which, through inhibition arachidonic acid, control the biosynthesis of prostaglandins and leukotrienes. The immune system is suppressed by corticosteroids due to a decrease in the function of the lymphatic system, a reduction in immunoglobulin and complement concentrations, the precipitation of lymphocytopenia, and interference with antigen-antibody binding. Betamethasone binds to plasma transcortin, and it becomes active when it is not bound to transcortin.

News Articles on Betamethasone

Viêm da tiếp xúc dị ứng  -  ‎Aug 4, 2009‎
...uống kháng histamine chống ngứa, thoa corticoid tại chỗ tại các sẩn dạng betamethasone dipropionate hay clobetasol propionate, tuy nhiên chỉ được thoa Người Lao Động

Different Epidural Injections May Relieve Low Back Pain Caudal ...  -  ‎Jun 26, 2009‎
...to receive CEIs with xylocaine, betamethasone dipropionate and betamethasone phosphate, or injections with xylocaine and water for injection (WFI). Modern Medicine

Calcipotriol Plus Betamethasone Dipropionate Formulation Effective ...  -  ‎Mar 10, 2009‎
By Jill Stein SAN FRANCISCO -- March 10, 2009 -- A scalp formulation combining calcipotriol plus betamethasone dipropionate markedly decreases itching DG News

AAD: Signal Transduction Inhibitor Has Activity in Psoriasis  -  ‎Mar 12, 2009‎
...active comparators, the 1.5% cream reduced lesion score by 46% versus 40% for calcipotriene and by 58% versus 44% for betamethasone dipropionate. MedPage Today

Use of Topical Corticosteroids for Dermatologic Conditions Reviewed  -  Jan 21, 2009
High-potency topical corticosteroids (groups 1 - 3) include augmented betamethasone dipropionate 0.05% and clobetasol propionate 0.05%. Medscape

New Once-Daily Combination Gel For Scalp Psoriasis  -  Nov 10, 2008
A study of the safety and efficacy of calcipotriol and betamethasone dipropionate scalp formulation in the long-term management of scalp psoriasis. Medical News Today (press release),

New Developments in Psoriasis Therapy  -  Nov 4, 2008
...of calcipotriol and betamethasone dipropionate is the current gold standard for the topical treatment of mild-to-moderate plaque-type psoriasis. Medscape (registration)

Xamiol gel provides relief for scalp psoriasis  -  Nov 11, 2008
Xamiol gel (pronounced "zamiol"), containing calcipotriol and betamethasone dipropionate, combines the effects of a Vitamin D-like ingredient to help News-Medical.net,

Glenmark Generics Gets ANDA Approval From US FDA For Betamethasone ...  -  Sep 25, 2008
...(RTTNews) - Glenmark Generics announced that its US subsidiary received ANDA approval from US FDA for Betamethasone Dipropionate Cream, 0.05% and stated RTT News,

Glenmark gets US FDA nod to mkt anti-inflammatory drug  -  Sep 25, 2008
...and Drug Administration approval for marketing and distribution of Betamethasone Dipropionate Cream, used in the treatment of inflammatory diseases. Business Standard,

Closing Bell  -  Sep 25, 2008
01:05 pm: Glenmark Generics Ltd's US subsidiary has received ANDA approval from the US Food and Drug Administration for Betamethasone Dipropionate Cream, Economic Times,

FDA Approves Taclonex Scalp(R) - Once Daily Therapy for Treatment ...  -  May 12, 2008
Taclonex Scalp(R) is a topical suspension containing a combination of calcipotriene 0.005% and betamethasone dipropionate 0.064% for the treatment of FOXBusiness

FDA Approvals: Taclonex Scalp, Abilify, Levaquin  -  May 22, 2008
May 22, 2008 — The US Food and Drug Administration (FDA) has approved calcipotriene hydrate plus betamethasone dipropionate topical suspension for the Medscape (subscription)

FDA Approves Psoriasis Treatment  -  May 19, 2008
Warner Chilcott, which holds an exclusive license to market the topical drug, plans to launch Taclonex Scalp (calcipotriene/betamethasone dipropionate) FDA news (subscription),

Warner Chilcott says FDA approves Taclonex Scalp, Once Daily ...  -  May 12, 2008
Taclonex Scalp, also called Xamiol outside the US, is a topical suspension containing a combination of calcipotriene 0.005% and betamethasone dipropionate RTT News,

Wal-Mart Launches Phase Two of Prescription Program With New $4 ...  -  Sep 27, 2007
QTY 60 SKIN CONDITIONS New BENZOYL PEROXIDE 4% CREAMY WASH QTY 171ML* BETAMETHASONE DIPROPIONATE 0.05% CREAM QTY 15GM BETAMETHASONE DIPROPIONATE 0.05% CNNMoney.com

Warner Chilcott and LEO Pharma Announce NDA Submission for ...  -  Jun 29, 2007
CNNMoney.comTaclonex Scalp(R) gel contains the same active ingredients as Taclonex(R) ointment (a combination of calcipotriene 0.005% and betamethasone dipropionate

`Bulge' veterans radiate spirit  -  Apr 22, 2007
Birmingham News,Lt. Wardlaw "Stumpy" Watson holds up a box containing a tube of betamethasone dipropionate. He hands the medication to his friend, 84-year old Pvt. Terrell

Calcipotriol/Betamethasone Has Good Safety Profile in Psoriasis ...  Oct 10, 2006
RHODES, GREECE -- October 10, 2006 -- Treatment with an ointment that contains calcipotriol 50 mcg/g plus betamethasone dipropionate 0.5 mg/g (Daivobet/Dovobet ... -DG News OINTMENT MORE EFFECTIVE THAN RECENTLY NICE-APPROVED BIOLOGICS ...  Aug 10, 2006
...prescribed ointment applied once a day, which is a combination of two existing treatments for psoriasis - calciptriol and betamethasone dipropionate - is more ... -ITNews

Combined ointment effective for psoriasis  Aug 11, 2006
...for different psoriasis treatments in the severe form of the condition -- the combination ointment of calciptriol and betamethasone dipropionate and three of ... -United Press International



Taclonex New Dual-Action Topical Therapy for Plaque Psoriasis Now ...  Apr 3, 2006
April 03, 2006 /PRNewswire/ -- Warner Chilcott and LEO Pharma announced today that Taclonex(R) (calcipotriene 0.005% and betamethasone dipropionate 0.064%), a ... - PharmaLive.com

Taclonex New Dual-Action Topical Therapy for Plaque Psoriasis Now ...  Apr 3, 2006
DENMARK -- April 3, 2006 -- Warner Chilcott and LEO Pharma announced today that Taclonex(R) (calcipotriene 0.005% and betamethasone dipropionate 0.064%), a once ... - DG News

Warner Chilcott Reports Operating Results for the Year and the ...  Mar 28, 2006
In July we realigned our sales forces in anticipation of the 2006 approvals of TACLONEX(R) (calcipotriene / betamethasone dipropionate) and our novel LOESTRIN(R ... - Black Enterprise

Topical therapies show promise for Psoriasis 06 Mar 2006
A combination of calcipotriene and betamethasone dipropionate, a vitamin D analogue and a potent corticosteroid, was recently approved by the FDA in an ... - News-Medical.net,

Taro Receives Tentative Approval for Augmented Betamethasone ...  Jan 26, 2006
...tentative approval from the US Food and Drug Administration ("FDA") for its Abbreviated New Drug Application for Betamethasone Dipropionate Lotion (Augmented ... - Genetic Engineering News

FDA Approves Taclonex (Calcipotriene/Betamethasone Dipropionate) ...  Jan 10, 2006
Taclonex is a topical ointment containing a combination of calcipotriene 0.005% and betamethasone dipropionate 0.064% for the treatment of psoriasis vulgaris ... - DG News

Taro tentatively OK'd for Diprolene  Jan 26, 2006
The company said the Food and Drug Administration approved Taro's generic version of Schering's augmented betamethasone dipropionate lotion, 0.05 percent. ... - United Press International

Burbs: Atlas Air CEO to step down  Jan 31, 2006
...of Hawthorne has received tentative approval from the US Food and Drug Administration for its new drug application for Betamethasone Dipropionate Lotion. ... - The Journal News.com

FDA Approves Taclonex(R) - Once Daily Therapy for Treatment of ...  Jan 10, 2006
Taclonex(R) is a topical ointment containing a combination of calcipotriene 0.005% and betamethasone dipropionate 0.064% for the treatment of psoriasis ... - PR Newswire

Brand Names/Synonyms:
Betamethasone Dipropionate is also known by the following brand names and/or synonymsAlphatrex; Bebate; Becort; Bedifos; Beta-Methasone; Beta-Methasone Alcohol; Beta-Val; Betacorlan; Betacortril; Betaderm; Betadexamethasone; Betafluorene; Betamamallet; Betametasona [Inn-Spanish]; Betametasone [Dcit]; Betamethasone; Betamethasone Alcohol; Betamethasone Base; Betamethasone Cream; Betamethasone Dipropionate; Betamethasone Sodium Phosphate; Betamethasone Valearate; Betamethasone Valerate; Betamethasone [Usan:Ban:Inn:Jan]; Betamethasonum [Inn-Latin]; Betamethasonvalerat Mikron.; Betamethazone; Betapredol; Betasolon; Betatrex; Betnelan; Betsolan; Celestene; Celestone; Celestone Syrup and Tablets; Cidoten; Dermabet; Desacort-Beta; Diproderm; Diprolene; Diprolene Af; Diprosone; Flubenisolone; HSDB 3015; Hormezon; Lotrisone; Luxiq; Luxiqo; Maxivate; Methazon; Rinderon; Rinderon A; Sch 4831; Uticort; Valisone; Valnac; Visubeta

Drug Category:
Betamethasone Dipropionate is categorized under the following by the FDA: Corticosteroid; Glucocorticoids; Anti-inflammatory, steroidal; Immunosuppressant; ATC:A07EA04; ATC:C05AA05; ATC:D07AC01; ATC:D07XC01; ATC:H02AB01; ATC:R01AD06; ATC:R03BA04; ATC:S01BA06; ATC:S01CB04; ATC:S02BA07; ATC:S03BA03

Dosage Forms:
Syrup; Tablet

Absorption:
Minimal if applied topically

Interactions:
Interactions for Betamethasone:
APRD00513_IN,txt



Chemical IUPAC Name:
9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one

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