Bactroban

This page contains recent news articles, when available, and an overview of Bactroban but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Bactroban
(when available)

Pharmacology and use:
Mupirocin, an antibiotic produced from Pseudomonas fluorescens, is structurally unrelated to any other topical or systemic antibiotics. Mupirocin is used to treat infection caused by Staphylococcus aureus and beta-hemolytic streptococci including Streptococcus pyogenes. This antibiotic has little, if any, potential for cross-resistance with other antibiotics. For the treatment of staphylococci nasal carriers

Mechanism Of Action:
Mupirocin reversibly binds to bacterial isoleucyl-tRNA synthetase, an enzyme which promotes the conversion of isoleucine and tRNA to isoleucyl-tRNA, resulting in the inhibition of bacterial protein and RNA synthesis.

News Articles on Mupirocin

Women can ignore most fibroids  -  ‎Aug 22, 2009‎
You can eliminate it by putting a dab of Bactroban Nasal ointment in the lowermost part of each nostril twice a day for five days (prescription required). Alexandria Town Talk

GlaxoSmithKline completa la compra de Stiefel Laboratories más de ...  -  ‎Aug 6, 2009‎
..."Estamos ansiosos de poder combinar los productos dermatológicos de prescripción de GSK --como 'Bactroban', 'Cutivate' y 'Altabax'-- con la cartera de ADN.es

Koupeme holÄ?iÄ?ku: Zvláštní péÄ?e  -  ‎Aug 19, 2009‎
NaruÅ¡ená kůže je náchylná ke vzniku zánÄ›tů - v tomto případÄ› je po dohodÄ› s lékaÅ™em vhodné používat mast s lokálnÄ› působícími antibiotiky (Bactroban, Žena.cz

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Treating insect bites and stings...and when to call the doctor  -  ‎Jun 19, 2009‎
If your doctor will call in a prescription strength ointment called Bactroban, then this may work better. It may take one or two days for this treatment to Examiner.com

Urticaria si impetigo  -  ‎Jun 16, 2009‎
Daca infectia se raspandeste, medicul v-ar putea prescrie antibiotice orale, precum si penicilina sau eritromicina sau un unguent cu mupirocina (Bactroban). City News

GSK acquires leading skincare specialist  -  20 Apr 2009
GSK's key dermatology brands include: Bactroban, Cutivate and the recently launched Altabax. Stiefel, part-owned by buyout firm Blackstone Group, CNN International

GSK buys derm firm Steifel  -  20 Apr 2009
GSK derm brands include Bactroban, Cutivate and Altabax. The GSK and Steifel brands would be combined in a global specialist group under the Steifel name, Medical Marketing and Media

12 ways to shrink your health care footprint  -  ‎Mar 29, 2009‎
For example, there's a generic form of mupirocin ointment, but as a cream, the antibiotic is available only as brand-name Bactroban. Chicago Daily Herald

Standard of care for MRSA infections  -  Dec 23, 2008
...use of mupirocin (Bactroban) and chlorhexidine (Hibiclens) for prevention and eradication of MRSA colonization of the patient and close family members. Clinical Advisor,

Recurrent boils demand persevering treatment  -  Dec 18, 2008
She should cover that part of the nose with a light coat of Bactroban (mupirocin) ointment twice a day. She must cover any draining boil with a dressing, SouthCoastToday.com,

Health Guidelines for Hajj and Umrah  -  21 Nov 2008
Treat scratches and even tiny cuts and fungal infections promptly with an antibiotic cream like Bactroban until they heal. Apply extra moisturiser to keep Impact News,

Ask the Doctor: There's lots you can do to tackle the pain of ...  -  Nov 10, 2008
And if medicines aren't also to blame, I'd suggest applying a little antibiotic cream inside the nose twice daily - Naseptin or Bactroban are the ones most Daily Mail,

Acute and Chronic Rhinosinusitis: Practical Clinical Treatment ...  -  Nov 5, 2008
Those patients are treated with a topical mupirocin (Bactroban®, GlaxoSmithKline) intranasally and that's all they require. Medscape (registration)

Antibiotic Ointment Might Reduce Risk of Dangerous Staph Infections  -  Oct 14, 2008
Mupirocin (also known by its brand name, Bactroban, which GlaxoSmithKline manufactures) is a topical antibiotic that is effective against several bacteria, Health Behavior News Service

Infection Rate Reduction Wins Recognition at Saint Clare's Health ...  -  Oct 6, 2008
Treatment for employees includes nasal Bactroban, Hibiclens showers, and treatment with oral antibiotics: either Rifampin, Doxycycline, or Bactrim DS, Nurse.com,

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Caution: 'Mersa' is one nasty little bacteria  -  Jul 20, 2008
Treatment consists of applying an antibiotic ointment, Bactroban, inside the nose with a cotton tip swab twice a day for five days. Orlando Sentinel,

Ronnie Polaneczky: People who should know, should know  -  Jul 15, 2008
Her son, who had a skin infection, was prescribed something called Bactroban Cream, a tiny tube of which cost $95. "We used that tube for one day, Philadelphia Daily News,

Rugby's New World Order!  -  Jul 27, 2008
Simply clean and dress her wound with Bactroban and send her on her way. Then there was the young girl with her boyfriend who looked like she was just "love Fiji Times,

Keeping kids healthy in the summer  -  Jun 4, 2008
...your doctor may suggest a topical over-the-counter antibiotic such as bacitracin or a prescription-strength antibiotic like Bactroban. CNN

MRSA -- Methicillin-resistant staphylococcus aureus  -  Feb 14, 2008
Topical mupirocin, or Bactroban, may be used in less severe cases. Oral medications that are commonly prescribed include Bactrim DS PlanetOut,

Wrestling team gets aggressive in fighting nasty staph infection  -  Feb 10, 2008
All 54 wrestlers and coaches had their noses swabbed morning, noon and night with Bactroban. The medicine has proved effective in eradicating staph. Beatrice Daily Sun,

P100m in smuggled textile, drugs seized  -  Jan 28, 2008
Raubasine, Mycostatin, Ninazol tablets, Terramycin, Bactroban ointment, Pharmadol, Approvel, Neurontin, Difenac and 10 bottles of unlabeled tablets. Manila Standard Today,

Flesh eating Staph in the news  -  Jan 16, 2008
One problem: Staph also tends to hide in the front of the nose, so carriers often have to apply Bactroban ointment locally to get the germs there. Blogger News Network

Preoperative Decolonization of Methicillin-resistant ...  -  Jan 11, 2008
1,2,27,28 Of these topical intranasal applications, mupirocin ointment (Bactroban Nasal, GlaxoSmithKline) has proven to be the most effective. Ortho SuperSite,

Sinus MRSA: What to do when Methicillin Resistant Staph Aureus ...  -  Nov 27, 2007
...(Bactroban®) The MRSA sinus patient with family members should take extra precaution to wash their hands regularly and cover their mouth and nose when PR Web (press release),

Spinal cord inflammation disrupts signals to, from brain  -  Nov 10, 2007
An antibacterial cream or ointment like Bactroban can put an end to the infection. Altabax, a new antibiotic ointment, is quite effective and can be used on SouthCoastToday.com,

Hospitals ready for MRSA threat  -  Nov 6, 2007
If the culture comes back positive, these patients are placed in contact isolation and start treatment with Bactroban and Hibiclenz, then are retested after Dothan Eagle,

An old infection gets new attention  -  Nov 4, 2007
...can usually be controlled with simple treatments that include drainage and/or oral and topical antibiotics, such as Bactrim and Bactroban, Wynn said. Savannah Morning News,

Rise in hospital infections prompts new health regulations  -  Oct 29, 2007
Now she's armed with Phisoderm soap, a prescription for Bactroban ointment for the nose and blue surgical gloves to prevent the chances of becoming infected Santa Cruz Sentinel,

Family endures 3-year battle with staph  -  Oct 20, 2007
In addition to the Clorox baths, the family must use a cotton swab to put Bactroban ointment in their nasal cavities. This, too, will go on for six months. The Tribune-Democrat,

What is impetigo?  -  Sep 24, 2007
Antibiotic creams or ointments, such as Fucidin or Bactroban, are usually effective after about one week of treatment. More severe infections may require an Irish Independent,

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Arpida Presents Preclinical Data on AR-2474 at ICAAC  -  Sep 21, 2007
F1-2100: The topical activity and potency of AR-2474 was compared with the gold standard mupirocin (Bactroban(R)) in two preclinical models of MRSA Earthtimes.org

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Freedom Challenge report  -  Jul 18, 2007
Supersport,...toothbrush, face wash and moisturizer and bactroban), but the rest didn’t matter anymore as “important� things become unimportant in the bigger picture.

These laboratories passengers presenting while on evidence.  -  02 Jul 2007
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These laboratories outbreaks were amplified by effective.  -  02 Jul 2007
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New Aerosol Formulas from California Lab Help Sinus Sufferers ...  -  Jun 4, 2007
PR Web (press release),Aerosol Science's ASL Pharmacy division has added Mupirocin (active ingredient in Bactroban®) and Mometasone (active ingredient in Nasonex®) to its

GlaxoSmithKline Announces Altargo® Approved In Europe For ...  -  Jun 4, 2007
Medical News Today (press release),These products include the topical antibacterial agent Bactroban® (mupirocin) as well as the oral agent Augmentin® (amoxicillin/clavulanate potassium).

The planning working life antiviral agents older.  -  Jun 16, 2007
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The project to report source cases relevant.  -  Apr 23, 2007
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Staph infection can turn deadly  -  Apr 22, 2007
Denver Post,Q: My doctor says I have a staph infection and prescribed Bactroban cream (mupirocen). I'd like more information about staph.

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GSK Announces FDA Approval Of Altabaxâ„¢ (retapamulin Ointment), 1%  -  Apr 16, 2007
Medical News Today (press release),These products include the topical antibacterial agent Bactroban® (mupirocin) as well as the oral agent Augmentin® (amoxicillin/clavulanate potassium).

GSK Announces FDA Approval Of Altabax(TM) (Retapamulin Ointment), 1%  -  Apr 14, 2007
Medical News Today (press release),These products include the topical antibacterial agent Bactroban(R) (mupirocin) as well as the oral agent Augmentin(R) (amoxicillin/clavulanate potassium).

Staph infection emerging as serious surfer ailment  -  Jan 6, 2007
OCRegister,..."If it's positive, it's straightforward to get rid of with Bactroban cream applied inside the nose for 10 days, and/or by 10 days of oral antibiotics to

GSK Receives Approvable Letter for Topical Antibiotic, Altabax(TM ...  -  Dec 22, 2006
Genetic Engineering News (press release),These products include the topical antibacterial agent Bactroban(R) (mupirocin) as well as the oral agent Augmentin(R) (amoxicillin/clavulanate potassium).

GSK Receives Approvable Letter for Topical Antibiotic, Altabax ...  -  Dec 22, 2006
Business Wire (press release),These products include the topical antibacterial agent Bactroban® (mupirocin) as well as the oral agent Augmentin® (amoxicillin/clavulanate potassium).

GSK Receives Approvable Letter for Topical Antibiotic, Altabax(TM ...  -  Dec 22, 2006
Genetic Engineering News (press release),These products include the topical antibacterial agent Bactroban(R) (mupirocin) as well as the oral agent Augmentin(R) (amoxicillin/clavulanate potassium).

GSK Receives Approvable Letter for Topical Antibiotic, Altabax ...  -  Dec 22, 2006
Business Wire (press release),These products include the topical antibacterial agent Bactroban® (mupirocin) as well as the oral agent Augmentin® (amoxicillin/clavulanate potassium).

ELBOW HAS THE EQUIVALENT OF HOUSEMAID'S KNEE  Sep 21, 2006
Applying a light coat of Bactroban nasal ointment (a prescription item) to the lower inside of both nostrils can generally evict staph from there. ... -Charlotte Sun-Herald

FOOD ALLERGY NOT TO BLAME FOR MOST STOMACH UPSETS  Aug 31, 2006
...infection. Bactroban ointment applied to the lower third of the inner nostrils can get rid of staph that often find a sanctuary there. ... -Charlotte Sun-Herald

CA-MRSA infections an increasing concern in early infancy  Aug 1, 2006
...or symptoms of systemic infection, cleansing of skin lesions and the use of topical antibacterial-containing ointment such as mupirocin (Bactroban) may be ... -AAP News (subscription)

Now's a good time to clean out your medicine cabinet  Jul 9, 2006
If your doctor will prescribe mupirocin ointment (Bactroban), you will have an even more powerful topical antibiotic available for skin infections. ... -Houston Chronicle

A Deadly Bacteria ; In Hospitalized Patients, an Infection Can Be ...  Jun 22, 2006
When applied inside the nostrils, an antibiotic ointment called Bactroban can effectively eliminate nasal colonization of MRSA, thus reducing the spread of the ... -International News Service



Doctors warned of new infection  Apr 17, 2006
Canterbury Health Laboratories clinical director Dr Mona Schousboe had said that a community-based strain of MRSA that was resistant to Bactroban, a topical ... - Stuff.co.nz





Study indicates students test positive for bacteria  Mar 9, 2006
In all but one of the wounds, the findings came back for the same strain. Those who tested positive were treated with Bactroban, an antibiotic nose spray. ... - Indiana Statesman

GlaxoSmithKline's Topical Antibacterial Retapamulin Accepted for ... Feb 14, 2006
...established heritage in the development of novel anti-infectives to meet clinical needs, including the topical antibacterial agent Bactroban® (mupirocin) as ... - Yahoo! News

Brand Names/Synonyms:
Bactroban is also known by the following brand names and/or synonymsBactoderm; Bactroban; Bactroban Nasal; Centany; MRC; Mupirocin; Mupirocine; PSEUDOMONIC ACID; Turixin

Drug Category:
Bactroban is categorized under the following by the FDA: Anti-bacterial Agents; Antibiotics; ATC:D06AX09; ATC:R01AX06

Dosage Forms:
Topical ointment, nasal spray

Absorption:
no measurable systemic absorption

Interactions:
Interactions for Mupirocin:

No information provided.





Chemical IUPAC Name:
13-[3,4-dihydroxy-5-[[3-(2-hydroxy-1-methyl-propyl)oxiran-2-yl]methyl]tetrahydropyran-2-yl]-12-methyl-10-oxo-tridec-11-enoicacid

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