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Albuterol sulfateThis page contains recent news articles, when available, and an overview of Albuterol sulfate but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.Overview: Albuterol sulfate (when available) Vincristine is a vinca alkaloid antineoplastic agent used as a treatment for various cancers including breast cancer, Hodgkin's disease, Kaposi's sarcoma, and testicular cancer. The vinca alkaloids are structurally similar compounds comprised of 2 multiringed units, vindoline and catharanthine. The vinca alkaloids have become clinically useful since the discovery of their antitumour properties in 1959. Initially, extracts of the periwinkle plant (Catharanthus roseus) were investigated because of putative hypoglycemic properties, but were noted to cause marrow suppression in rats and antileukemic effects in vitro. Vincristine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death. Vincristine has some immunosuppressant effect. The vinca alkaloids are considered to be cell cycle phase-specific. For treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, acute panmyelosis Mechanism Of Action: The antitumor activity of Vincristine is thought to be due primarily to inhibition of mitosis at metaphase through its interaction with tubulin. Like other vinca alkaloids, Vincristine may also interfere with: 1) amino acid, cyclic AMP, and glutathione metabolism, 2) calmodulin-dependent Ca2+-transport ATPase activity, 3) cellular respiration, and 4) nucleic acid and lipid biosynthesis. News Articles on Vincristine Spring is here, and so are allergies - May 14, 2008 Both medications use albuterol sulfate as their active ingredient and individuals who rely on inhalers should be able to make the change without foreseeable Contra Costa Times, Teva enters drug alliance with UCB in USA - Jan 18, 2008 The initial product to be jointly promoted is Teva's ProAirHFA (albuterol sulfate) Inhalation Aerosol, which is the number-one branded hydrofluroalkane Therapeutics Daily (subscription) (press release), Teva Enters Into US Respiratory Collaboration Deal With UCB - Jan 16, 2008 The first product to be jointly promoted by the two companies in the US is Teva's ProAirHFA or albuterol sulfate Inhalation Aerosol. Trading Markets (press release), Takeda, Dey Pay Alabama $6.75 Million in Medicaid Lawsuit - Jan 18, 2008 ...and its claim against Dey involved a number of drugs prescribed primarily for pulmonary diseases and asthma, such as albuterol sulfate and ipratropium FDA news (subscription), Market Report -- In Play (TEVA) - Jan 16, 2008 The initial product to be jointly promoted in the US is Teva's ProAir HFA (albuterol sulfate) Inhalation Aerosol. Additionally, the agreement will provide MSN Money Watson to Sell Generic DuoNeb - Jan 10, 2008 Dey’s DuoNeb (ipratropium bromide/albuterol sulfate) inhaled solution is indicated for treating bronchospasm associated with chronic obstructive pulmonary FDA news (subscription), Teva Specialty Pharmaceuticals and UCB Announce US Respiratory ... - Jan 16, 2008 The initial product to be jointly promoted in the US is Teva's ProAir(R)HFA (albuterol sulfate) Inhalation Aerosol. ProAir(R)HFA is the number-one branded PharmaLive.com (press release), Schering-Plough: Mass Court Finds No Liability For Warrick Unit - Nov 5, 2007 ...to class plaintiffs, reversing a prior decision of limited liability against Warrick for one form of a generic product, albuterol sulfate solution. CNNMoney.com Schering-Plough Reports US District Court for District of ... - Nov 5, 2007 ...but found limited liability against Warrick with respect to one form of a generic product, albuterol sulfate solution, in the years 1998 and 1999. CNNMoney.com Schering-Plough: artificial prices case highlights an industry ... - Nov 6, 2007 ...was exonerated of all liability; however, a question mark remained over Warrick's generic respiratory drug albuterol sulfate for the period 1998–99. Pharmaceutical Business Review Watson Receives FDA Approval for Generic Accuneb(R) - Sep 26, 2007 Watson intends to launch its albuterol sulfate inhalation product immediately. Albuterol sulfate is the generic equivalent to Dey, LP's AccuNeb(R) CNNMoney.com Watson Pharma gets generic AccuNeb OK - Sep 26, 2007 The company received 180 days of marketing exclusivity for its albuterol sulfate inhalation solution in 0.021 percent and 0.042 percent base strengths, CNNMoney.com Genzyme And Bayer Schering Pharma Initiates Phase 3 Trial Of ... - Sep 26, 2007 Watson plans to unveil its albuterol sulfate inhalation product immediately and to begin its market exclusivity upon commercial launch. Albuterol sulfate is RTT News, Watson Pharmaceuticals Inc announces FDA approval for generic Accuneb - Sep 27, 2007 Albuterol sulfate is the generic equivalent to Dey LP's AccuNeb Inhalation Solution, which is indicated for the relief of bronchospasm in patients two to 12 Trading Markets, Watson Pharma Gets FDA Approval To Market Generic Accuneb For ... - Sep 26, 2007 The Corona, California-based company had filed with the FDA an Abbreviated New Drug Application for albuterol sulfate inhalation solution in the 0.021% base Trading Markets, UPDATE 1-Watson gets FDA nod to sell generic asthma inhaler - Sep 26, 2007 The company said it intended to launch the inhalation product, albuterol sulfate inhalation solution, immediately and will receive 180 days of marketing Reuters Laws Of Physics Don't Apply To Ethics - Jul 18, 2007 Nebraska StatePaper.com,The price of the generic drug albuterol sulfate was inflated “in a range of 100 percent to 800 percent� by “Warrick, a subsidiary of Schering-Plough. Schering-Plough Reports on Favorable Rulings in AWP Case By US ... - Jun 27, 2007 PR-GB.com (press release),Although damages claimed against the company for the Warrick albuterol sulfate solution product are quite limited, the company said it is considering Schering-Plough: Court dismisses claims in suit - Jun 21, 2007 MarketWatch...it disagreed with the court's finding of limited liability against Warrick with respect to one form of a generic product, albuterol sulfate solution, 3 Drug Makers Are Convicted in Reimbursement Overcharges - Jun 22, 2007 Tuscaloosa News (subscription),Warrick, a subsidiary of Schering-Plough, which is based in Kenilworth, NJ, inflated average wholesale prices for its generic drug albuterol sulfate in a Drug prices ruled too high - Jun 22, 2007 Worcester Telegram,Schering-Plough’s subsidiary Warrick inflated average wholesale prices for its generic drug albuterol sulfate between 100 percent and 800 percent, The Confusion with Sulfa, Sulfite and Sulfate Allergies - May 1, 2007 About - News & Issues,Sulfates are "salts" of various medications, such as albuterol sulfate nebulizer medication used to treat asthma. These medications usually do not contain Teva Partners with Asthma Foundation and NBA to Go Pro for Asthma ... - Apr 2, 2007 American Digital Networks (press release),...provided by IVAX Laboratories' line of respiratory products, including the recently launched ProAir(R) HFA (albuterol sulfate) Inhalation Aerosol. Allergy & Asthma Network Mothers of Asthmatics Supports FDA's ... Mar 14, 2006 Albuterol MDIs are now available in several HFA formulations, including Proventil(r) HFA, Ventolin(r) HFA and Albuterol Sulfate HFA. ... - U.S. Newswire A warning on asthma drugs Mar 14, 2006 The medications most likely to be mimicked are Albuterol sulfate, manufactured by Nephron Pharmaceuticals and Warrick Pharmaceuticals; Xopenex, a product of ... - Newsday FDA Approvals: HepaGam B, Xibrom, Proair HFA Mar 1, 2006 ...of ocular pain in patients who have undergone cataract extraction; and an expanded indication for chlorofluorocarbon-free albuterol sulfate inhalation aerosol ... - Medscape (subscription) Brand Names/Synonyms: Albuterol sulfate is also known by the following brand names and/or synonymsIndole alkaloid; LCR; Leurocristine; Onco TCS; Oncovin; VCR; VIN; Vincasar PFS; Vincrex; Vincristina [DCIT]; Vincristine; Vincristine Sulfate; Vincristine Sulfate PFS; Vincristinum [INN-Latin]; Vincrstine; Vincrystine; Vinkristin; 22-Oxovincaleukoblastine; EINECS 200-318-1; Oncovin (1:1 sulfate salt); Vincaleukoblastine, 22-oxo-; Vincasar (1:1 sulfate salt); Vincrex (1:1 sulfate salt); Z-D-Val-Lys(Z)-OH Drug Category: Albuterol sulfate is categorized under the following by the FDA: Antineoplastic Agents; ATC:L01CA02 Dosage Forms: LIQUID; SOLUTION Absorption: Not Available Interactions: Interactions for Vincristine: The simultaneous oral or intravenous administration of phenytoin and antineoplastic chemotherapy combinations that included vincristine sulfate has been reported to reduce blood levels of the anticonvulsant and to increase seizure activity. Dosage adjustment should be based on serial blood level monitoring. The contribution of vincristine sulfate to this interaction is not certain. The interaction may result from reduced absorption of phenytoin and an increase in the rate of its metabolism and elimination. Chemical IUPAC Name: Not Available : |
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