Albuterol

This page contains recent news articles, when available, and an overview of Albuterol but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Albuterol
(when available)

Pharmacology and use:
Vincristine is a vinca alkaloid antineoplastic agent used as a treatment for various cancers including breast cancer, Hodgkin's disease, Kaposi's sarcoma, and testicular cancer. The vinca alkaloids are structurally similar compounds comprised of 2 multiringed units, vindoline and catharanthine. The vinca alkaloids have become clinically useful since the discovery of their antitumour properties in 1959. Initially, extracts of the periwinkle plant (Catharanthus roseus) were investigated because of putative hypoglycemic properties, but were noted to cause marrow suppression in rats and antileukemic effects in vitro. Vincristine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death. Vincristine has some immunosuppressant effect. The vinca alkaloids are considered to be cell cycle phase-specific. For treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, acute panmyelosis

Mechanism Of Action:
The antitumor activity of Vincristine is thought to be due primarily to inhibition of mitosis at metaphase through its interaction with tubulin. Like other vinca alkaloids, Vincristine may also interfere with: 1) amino acid, cyclic AMP, and glutathione metabolism, 2) calmodulin-dependent Ca2+-transport ATPase activity, 3) cellular respiration, and 4) nucleic acid and lipid biosynthesis.

News Articles on Vincristine

Lincare Holdings Inc. Announces First Quarter 2009 Financial Results  -  20 Apr 2009
Lower Medicare pricing, primarily for the drug albuterol, was implemented on April 1, 2008 by the Centers for Medicare and Medicaid Services ("CMS") PR Newswire (press release)

Beyond the Basics: Electrolyte Disturbances  -  20 Apr 2009
Nebulized albuterol (Ventolin) is given in a dose of 10 to 20 mg. Sodium bicarbonate is not recommended to lower potassium, but remains a viable treatment EMS Magazine

Link Could Exist Between Arthritis Drug, Pediatric Cancer  -  ‎Apr 14, 2009‎
According to the FDA, CFC-propelled albuterol inhalers are being phased out because they are harmful to the environment in that they contribute to the ADVANCE for LPNs

Combo inhaler to help asthma patients  -  ‎Apr 15, 2009‎
WASHINGTON: People with chronic asthma have been offered a new hope in the form of an inhaler that contains two medicines. Asthma sufferers use maintenance Times of India

Study Finds Smoking Marijuana Not Linked to Risk of COPD However ...  -  ‎Apr 15, 2009‎
...analyzed data from 878 subjects aged 40 years and older, who reported on their smoking history and underwent spirometric testing with albuterol. Modern Medicine

Riverheads French classes find international pen pals  -  ‎Mar 29, 2009‎
They are looking for ways to modify the response of immune cells by using albuterol, a medication that is commonly prescribed to treat human asthma. Staunton News Leader

Study Uses GPS To Help Asthma Patients  -  ‎Apr 16, 2009‎
In the study, the GPS device attaches to a regular albuterol inhaler and tracks the frequency and location of every inhaler use. WISC

Balancing the Benefits and Risks of Inhaled Long-Acting Beta ...  -  ‎Apr 15, 2009‎
...had shown a not-quite-significant increase in the rate of asthma-related deaths associated with salmeterol as compared with short-acting albuterol. New England Journal of Medicine (subscription)

Seasonal allergies increase in spring  -  ‎Apr 14, 2009‎
Martin said strong winds and dust devils in Stillwater cause his asthma to flare up so much that he has to carry his Albuterol inhaler with him. Daily O'Collegian

Programs offer way to cut costs for prescription drugs  -  ‎Apr 15, 2009‎
She got free samples of some other allergy pills, and a ProAir albuterol inhaler from doctors. But when Taegan's pediatrician last fall also prescribed an Cherry Hill Courier Post

Esomeprazole treatment does not improve poorly controlled asthma  -  ‎Apr 14, 2009‎
Secondary outcomes included the results of spirometry before and after albuterol 180 mcg inhalation and changes in asthma symptom, quality-of-life, Modern Medicine

Janitors, science center battle over unionization  -  ‎Apr 7, 2009‎
Although he is asthmatic, he does not go to the doctor and does not have a prescription for Albuterol, the fast-acting bronchodilator that could help him Pittsburgh Post Gazette

Efficacy of Budesonide or Montelukast Treatment of Wheezing ...  -  ‎Apr 1, 2009‎
Patients in all three groups received albuterol during a RTI. Parents of study children were instructed to begin a planned seven-day course of the oral and AAP Grand Rounds (registration)

Childhood Asthma : Millions of children left untreated  -  ‎Apr 8, 2009‎
...“We have bronchodilators, including ones with the drug albuterol, that target the symptoms of asthma and make breathing easier in an acute situation,� says Little About

RE: I just don't believe them. Why do you?  -  ‎Mar 28, 2009‎
Personally, in almost 30 years I have never used my insurance other than for a few antibiotics and albuterol inhalers on the two occasions I’ve had OmniNerd

Fluticasonfuroat: Gute Asthmakontrolle bei nur einmal täglicher Gabe  -  ‎Apr 7, 2009‎
Alle Patienten konnten bei Bedarf ein kurz wirksames Beta-Mimetikum (Albuterol) als Notfallmedikation einsetzen, um eventuelle Asthmasymptome zu behandeln. Informationsdienst Wissenschaft (Pressemitteilung)

Teva's Qvar 'could benefit asthma patients'  -  18 Mar 2009
Last year, the US Food and Drug Administration approved Teva's ProAir HFA albuterol inhaler for use by asthma patients as young as four years old. Hays Pharma

Long-Acting Beta Agonist Plus Inhaled Corticosteroid Beneficial in ...  -  18 Mar 2009
Albuterol was provided as needed. In children, changes in evening FEF 25%-75% were 3.6%, -3.1%, and -3.3% for BUD/FM twice daily, BUD/FM once daily, DG News

VIDEO: Consistent Exercise Recommended After Heart Attack, Obesity ...  -  18 Mar 2009
Patients treated between 2004 and 2007 showed significantly lower use of oral corticosteroids and rescue albuterol than those treated from 1993 to 1997. Insidermedicine

Doctors Hear Gripes About HFA Inhalers  -  ‎Mar 11, 2009‎
By Kristina Fiore, Staff Writer, MedPage Today The griping has become more common since a ban on chlorofluorocarbons (CFCs) in albuterol metered dose MedPage Today

'I don't remember anything,' Fry says  -  ‎Mar 12, 2009‎
McEwen was known to use Albuterol. If convicted, Fry faces up to 50 years in prison. Testimony is scheduled to continue today. The trial is expected to wrap Iowa City Press Citizen

Our Night at Akron Children's  -  ‎Mar 11, 2009‎
Another albuterol nebulizer treatment and oral steroids were given but her lungs still weren't at a state to make them comfortable sending her home. Youngstown Vindicator

FDA Safety Changes: Combivent, Qualaquin, Sucraid  -  ‎Mar 4, 2009‎
On November 10, 2008, the FDA approved safety labeling revisions for ipratropium bromide and albuterol sulfate inhalation aerosol (Combivent; Medscape

Parents seeking millions against school district for asthma attack ...  -  ‎Mar 8, 2009‎
Four school employees gathered around the dark-eyed, gap-toothed 10-year-old, giving comfort, working to calm her, urging puffs on an Albuterol inhaler, TheNewsTribune.com

New Treatments Improve Control for Severe Asthma  -  ‎Mar 16, 2009‎
Today's group turned to their rescue (albuterol) inhaler about half as often as the group from the '90s did, and their lung function scores were higher. U.S. News & World Report

Asthma Patients Get Scant Response to Problems with New Inhalers  -  ‎Feb 22, 2009‎
The HFA "emergency" inhalers give patients the same dose of albuterol as CFC inhalers and are a "safe and effective" alternative for the more than 40 Consumer Affairs

from the AAP Division of Health Care Finance and Quality Improvement  -  ‎Feb 27, 2009‎
My practice uses albuterol or Xopenex unit dose when administering breathing treatments to patients. Since the beginning of January, we have been receiving AAP News (subscription)

Wegmans to offer $4 prescription program  -  ‎Feb 25, 2009‎
Among the drugs covered in the $4 program are the diabetes medication metformin, cholesterol medications lovastatin and pravastatin, albuterol nebulizers Elmira Star-Gazette

'10 Americans' hits home for Mill Valley mom  -  ‎Mar 15, 2009‎
...points out that many popular drugs - Paxil, Cialis and Albuterol, among them - have very real therapeutic effects at the same or lower concentrations. San Francisco Chronicle

Air particles raise risk of childhood asthma  -  ‎Feb 27, 2009‎
...of children's homes causes increased asthma-like symptoms, as well as an increased use of medications, like albuterol inhalers, that protect the airway. Johns Hopkins News-Letter

Mometasone Inhaler Use Reduces Use of Rescue Medication in ...  -  ‎Mar 16, 2009‎
Baseline albuterol rescue use was 1.3 puffs daily in all treatment groups. Effect of treatment on rescue medication use, as recorded in daily diaries and DG News

Inhaled Corticosteroids Helpful for Infants and Preschoolers With ...  -  ‎Mar 9, 2009‎
...changes in symptoms score, pulmonary function (peak expiratory flow and forced expiratory volume in 1 second [FEV1]), or use of albuterol. Medscape

RSV cases spiked in late February  -  ‎Mar 10, 2009‎
If the virus triggers bronchial spasms with harsh coughing, albuterol breathing treatments may be prescribed. Dr. Sonia Reidy, at Phoenix Children’s East Valley Tribune

Asthma symptom of Churg-Strauss  -  ‎Mar 6, 2009‎
I now have asthma and am on prednisone again as well as an albuterol inhaler. Whenever I have an asthma attack, my doctor increases the prednisone dose and Pasadena Star-News

10-K: WATSON PHARMACEUTICALS INC  -  ‎Feb 23, 2009‎
...including fentanyl transdermal patch (launched at the end of the third quarter of 2007), albuterol sulfate (launched in the fourth quarter of 2007), MarketWatch (press release)

Death takes a holiday...in my esophagus  -  ‎Mar 5, 2009‎
I jammed the key home, ripped opened the door, tore at the glove box, and took a hit of albuterol. And another. And another. And another. And another. Azle News

Good News For Parents: Newer Asthma Medications Make The Grade  -  ‎Mar 14, 2009‎
Additionally, the present cohort had higher FEV1, required less albuterol and had fewer intubations in the past. The study authors suggest these findings Medical News Today (press release)

Asthma inhalers: Which one's for you?  -  ‎Mar 2, 2009‎
These medications, including albuterol (Proventil, Ventolin) and pirbuterol (Maxair), provide immediate relief of asthma symptoms. WTHI

RSV is extremely contagious, affects kids  -  ‎Feb 23, 2009‎
..."They can be given xopenex albuterol (to help breathing) and sometimes, steroids. Parents are warned to consult a physician before giving a child any Defiance Crescent News

Breathing at a Cost  -  ‎Feb 26, 2009‎
Hospitals have been using metered-dose inhalers with generic albuterol because they are as effective as nebulizers but less expensive, Millard said. ADVANCE for LPNs

Asthma Drugs Need to be Maintained for Continued Benefit  -  ‎Feb 19, 2009‎
All children received albuterol, a bronchodilator, and oral corticosteroids as needed for asthma symptoms. This study followed up with the children nearly Drug Discovery & Development

Diagnosis and Treatment of Sleep Disorders in Older Adults  -  ‎Feb 25, 2009‎
...beta-blockers, alpha-blockers, methyldopa, reserpine), respiratory medications (eg, theophylline, albuterol), bronchodilators, calcium channel blockers, Focus (subscription)

Nuevas regulaciones fuerzan a asmáticos a revisar su tratamiento  -  ‎Mar 15, 2009‎
La mayoría de los inhaladores proveen albuterol, un broncodilatador de acción rápida que relaja los músculos que rodean las vías de aire y que, Bajo el Sol

Parents fear impact of possible school nurse cuts  -  04 Feb 2009
..."My son has asthma and requires an albuterol inhaler," says Debbie Jackson. Nurses in Bibb County schools saw more than 14500 students last semester alone. Today's MGT,

GSK and Theravance announce positive phase 2b results for once ...  -  04 Feb 2009
All patients were permitted to use a short-acting beta-agonist (albuterol) as rescue medication to relieve symptoms of asthma as needed. PipelineReview.com (press release),

Catching your breath: How to deal with winter asthma  -  Feb 2, 2009
..."I guess when it's below zero outside, I'll use my Albuterol (rescue inhaler) or something, and then I'm fine for the rest of the day once I get used to it Daily Camera,

Pathogens & People: RSV vaccine a challenge for scientists  -  Feb 1, 2009
Bronchodilators such as Albuterol have sometimes been used, and the anti-viral drug Ribavirin has been tried in some studies, but its overall usefulness is Annapolis Capital,

Inhaler Ban Leads to Confusion, Concern for Some Patients  -  Jan 22, 2009
HFA-propelled albuterol inhalers available in the United States include Proair HFA Inhalation Aerosol (Teva), Proventil HFA Inhalation Aeroso Medscape

GSK, Wal-Mart sell $9 rescue inhaler  -  Jan 20, 2009
The inhalers contain albuterol, a drug that provides asthma and emphysema sufferers with immediate relief. They are powered by hydrofluoroalkane, or HFA, News & Observer,

Government Bans Generic Rescue Inhalers  -  Jan 29, 2009
When that happens, Gordon turns to the drug Albuterol, also known as a rescue inhaler. "The rescue inhaler is immediate acting when someone is short of WJZ,

Steroids and child wheeze  -  Jan 27, 2009
Children were treated according to the guidelines issued by the British Thoracic Society – for instance they were given oxygen and albuterol as required. Border Counties Advertizer,

Good news and bad news on health insurance  -  Jan 8, 2009
They had to go with the older, cruder drug, generic albuterol. Now that's fine, except for one thing. Even when not taking prednisone, a dose of albuterol, The State,

New asthma inhalers are ozone-friendly  -  Jan 14, 2009
Most of the issue is about these quick-acting rescue inhalers, which are mostly Albuterol. They come in a canister, and to deliver the medicine out of the Indianapolis Star,

Inhalers offer price relief, too  -  Jan 14, 2009
31, US companies are banned from manufacturing albuterol inhalers that use chlorofluorocarbons as a propellant. The cost of the old inhalers averaged Tulsa World,

What's the evidence for quick-relief inhalers to relieve wheezing ...  -  Jan 21, 2009
Controlled trial of nebulized albuterol in children younger than 2 years of age with acute asthma. Pediatrics. 1992; 89: 133-137. Ploin D, Chapuis FR, guardian.co.uk,

What's the evidence for ipratropium from an inhaler for more ...  -  Jan 21, 2009
Randomized trial of the addition of ipratropium bromide to albuterol and corticosteroid therapy in children hospitalized because of an acute asthma guardian.co.uk,

A Medical Mystery — Constipation  -  Jan 21, 2009
Her medications consisted of phenytoin, tegaserod, fluticasone–salmeterol, and an albuterol inhaler. What is the diagnosis? Editor's note: We invite our New England Journal of Medicine (subscription),

Economically Disadvantaged Asthma Sufferers Breathe Easier with ...  -  Jan 15, 2009
The US FDA/EPA set December 31, 2008, as the deadline for phasing out albuterol inhalers containing ozone-depleting CFC-based propellants and replacing them WELT ONLINE,

Harvard Ambulance Service gets award  -  Feb 2, 2009
Basic EMTs also administer low-level medications — aspirin for heart attack, albuterol for severe asthma, glucose for diabetic crises or activated charcoal Harvard Post,

Hark, is that a bark? Yes, it's croup  -  Jan 17, 2009
For the first three years of his life, every cold meant wheezing so bad that we became well acquainted with Albuterol, Qvar and nebulizers. Kid No. The Oregonian - OregonLive.com,

The FDA Is Trying To Kill Me  -  Jan 11, 2009
Albuterol CFC inhalers are to Asthmatics what insulin is to Diabetics. A life-line. This is the only comparison that I can think of. OpEdNews,

VIDEO: Oral Prednisolone Does Not Benefit Children Suffering from ...  -  Jan 21, 2009
...of time they spent in hospital, scores on measures of respiration or symptoms, or use of albuterol, a drug that is inhaled to quickly open the lungs. Insidermedicine,

MediciNova Reports Interim Phase II Data From MN-221 Emergency ...  -  Jan 12, 2009
All patients received standardized care consisting of inhaled albuterol, ipratropium and oral steroid treatment. No safety concerns with adding MN-221 to GlobeNewsWire (press release),

Peds Respiratory Emergencies  -  Jan 8, 2009
Treatments: Administer corticosteroids (oral, IM or IV) and nebulizer treatments with bronchodilators such as albuterol, also known as "rescue medication. ADVANCE for LPNs,

Schering-Plough Reports Financial Results for 2008 Fourth Quarter ...  -  Feb 3, 2009
SUBOXONE 52 57 (9%) 230 220 5% PROVENTIL / ALBUTEROL CFC 63 41 52% 190 207 (8%) CERAZETTE c/ 44 20 N/M 185 20 N/M LIVIAL c/ 40 24 N/M 183 24 N/M ASMANEX PR Newswire (press release),

What treatments work for bronchiolitis?  -  Jan 21, 2009
Randomized, placebo-controlled trial of albuterol and epinephrine at equipotent beta-2 agonist doses in acute bronchiolitis. Pediatric Pulmonology. guardian.co.uk,

Sepracor Reports Fourth Quarter and Full-Year 2008 Operating Results  -  Jan 28, 2009
...a bundled payment calculation methodology for XOPENEX Inhalation Solution and generic albuterol inhalation solution, which was effective July 1, 2007. Trading Markets (press release),

Auction houses agree to uniform guidelines  -  Jan 21, 2009
...drugs and no more than one corticosteroid. w Prohibit administration of any bronchodilator, including but not limited to clenbuterol and albuterol, Daily Racing Form (registration),

Treatment options for respiratory infections  -  Jan 27, 2009
For example, write out a detailed “viral� prescription of rest, fluids, OTC analgesics, and albuterol. At the same time, write out a backup plan informing Clinical Advisor,

Annual bronchiolitis epidemic has begun  -  Jan 10, 2009
Bronchodilators such as albuterol usually are not effective, and current guidelines argue against their routine use. Ear infection is the most common Times,

A good dose of precaution can help avoid drug harm, says Yukon family  -  Jan 22, 2009
PHOTO BY ANN KELLEY, THE OKLAHOMAN Koenig said her 6-month-old, Story, was prescribed Albuterol for a respiratory virus with specific instructions from her NewsOK.com,

Oral Prednisolone for Preschool Children with Acute Virus-Induced ...  -  Jan 21, 2009
Secondary outcomes were the score on the Preschool Respiratory Assessment Measure, albuterol use, and a 7-day symptom score. New England Journal of Medicine (subscription),

Ban On CFC Inhalers Goes Into Effect - ACSH Helps Asthma Patients ...  -  Jan 15, 2009
Most inhalers deliver the drug albuterol, a fast-acting bronchodilator that relaxes the muscles surrounding the airways in order to quickly relieve asthma Medical News Today (press release),

Atemnotanfälle: Kortikoide oral ineffektiv, inhalativ zu riskant  -  Jan 22, 2009
In der Klinik wurden die Kinder zunächst mit dem Betamimetikum Albuterol behandelt. Sofern sich der Zustand stabilisierte und die Kinder keine Deutsches Ärzteblatt,

Brand Names/Synonyms:
Albuterol is also known by the following brand names and/or synonymsAH 3365; Accuneb; Aerolin; Albuterol; Albuterol Sulfate; Albuterol Sulfate Hfa; Asmaven; Broncovaleas; Cetsim; Cobutolin; Ecovent; Loftan; Proventil; Proventil Inhaler; Proventil-Hfa; Rotahaler; Salbulin; Salbutamol; Salbutamol Free Base; Salbutamol Sulfate; Salbutamol Sulphate; Salbutard; Salbutine; Salbuvent; Solbutamol; Sultanol; Venetlin; Ventalin Inhaler; Ventolin; Ventolin Hfa; Ventolin Inhaler; Ventolin Rotacaps; Volma; Volmax; Xopenex; Xopenex Hfa

Drug Category:
Albuterol is categorized under the following by the FDA: Adrenergic beta-Agonists; Tocolytic Agents; Bronchodilator Agents; ATC:R03AC

Dosage Forms:
ORAL SOLUTION; SYRUP; TABLETS; EXTENDED-RELEASE TABLETS; INJECTION (Intramuscular, Intravenous)

Absorption:
Systemic absorption is rapid following aerosol administration

Interactions:
-->Interactions for Albuterol:

Other short-acting sympathomimetic aerosol bronchodilators should not be used concomitantly with albuterol. If additional adrenergic drugs are to be administered by any route, they should be used with caution to avoid deleterious cardiovascular effects.

Monoamine Oxidase Inhibitors or Tricyclic Antidepressants: Albuterol should be administered with extreme caution to patients being treated with monoamine oxidase inhibitors or tricyclic antidepressants, or within 2 weeks of discontinuation of such agents, because the action of albuterol on the vascular system may be potentiated.

Beta-Blockers: Beta-adrenergic receptor blocking agents not only block the pulmonary effect of beta-agonists, such as VENTOLIN Inhalation Aerosol, but may produce severe bronchospasm in patients with asthma. Therefore, patients with asthma should not normally be treated with beta-blockers. However, under certain circumstances, e.g., as prophylaxis after myocardial infarction, there may be no acceptable alternatives to the use of beta-adrenergic blocking agents in patients with asthma. In this setting, cardioselective beta-blockers could be considered, although they should be administered with caution.

Diuretics: The ECG changes and/or hypokalemia that may result from the administration of nonpotassium-sparing diuretics (such as loop or thiazide diuretics) can be acutely worsened by beta-agonists, especially when the recommended dose of the beta-agonist is exceeded. Although the clinical significance of these effects is not known, caution is advised in the coadministration of beta-agonists with nonpotassium-sparing diuretics.

Digoxin: Mean decreases of 16% to 22% in serum digoxin levels were demonstrated after single-dose intravenous and oral administration of albuterol, respectively, to normal volunteers who had received digoxin for 10 days. The clinical significance of these findings for patients with obstructive airway disease who are receiving albuterol and digoxin on a chronic basis is unclear. Nevertheless, it would be prudent to carefully evaluate the serum digoxin levels in patients who are currently receiving digoxin and albuterol.

 


 




Chemical IUPAC Name:
2-(hydroxymethyl)-4-(1-hydroxy-2-tert-butylamino-ethyl)-phenol

:
 
Web health.mongabay.com/health



Health Home | Conditions | Cancer | Medications | Surgery | Vaccines

mongabay.com


Disclaimer:

Contact a physician with regard to health concerns. Email requests for further health information will be discarded.

The materials contained on this Web site are for informational purposes only and do not constitute health or medical advice. Use of information on this site does not create or constitute any kind of agreement or contract between you and the owners or users of this site, the owners of the servers upon which it is housed, or anyone else who is in any way connected with this site.

Many links on health.mongabay.com/health lead to other sites. health.mongabay.com/health does not sponsor, endorse or otherwise approve of the materials appearing in such sites. Nor is health.mongabay.com/health responsible for dead or misdirected links.


COPYRIGHT 2007 MONGABAY.COM