Alavert

This page contains recent news articles, when available, and an overview of Alavert but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Alavert
(when available)

Pharmacology and use:
Loratadine, a non-sedating H1-blocker similar in structure to cyproheptadine and azatadine, is used to treat seasonal allergic rhinitis. Unlike other H1-blockers, loratidine does not penetrate the CNS effectively and has a low affinity for CNS H1-receptors. For the relief of nasal and non-nasal symptoms of seasonal allergic rhinitis and for the treatment of chronic idiopathic urticaria in patients 2 years of age or older

Mechanism Of Action:
Like other H1-blockers, loratadine competes with free histamine for binding at H1-receptors in the GI tract, uterus, large blood vessels, and bronchial muscle. Loratadine also has a weak affinity for acetylcholine and alpha-adrenergic receptors.

News Articles on Loratadine

Surviving Summer allegies  -  ‎Aug 8, 2009‎
Examples of second generation antihistamines are brand names like Claritin and Alavert which contain Loratadine, and Zyrtec which contains cetirizine. Examiner.com

Ragweed allergies are in full bloom  -  ‎Aug 27, 2009‎
Look for loratadine (Claritin and Alavert) or cetirizine (Zyrtec). For itchy eyes, try Zaditor. Scott said Visine and similar products shouldn't be used for Kansas.com

What Is Hay Fever? What Is Allergic Rhinitis? What Causes Hay Fever?  -  ‎Aug 14, 2009‎
Examples of OTC antihistamines include loratadine (Claritin, Alavert) and cetirizine (Zyrtec). Examples of prescription antihistamines include Fexofenadine Medical News Today

AdPerk and Rite Aid Innovate the Traditional Advertising ...  -  ‎Aug 7, 2009‎
...vendors (including Procter & Gamble, Kimberly-Clark, L'Oreal, Johnson & Johnson, Wyeth) and major brands (including Olay®, HUGGIES®, AVEENO®, Alavert®). Emediawire (press release)

Allergic rhinitis: market evolution  -  ‎Apr 3, 2009‎
In the United States, loratadine (Claritin and Alavert) and cetirizine (Zyrtec) have been the major antihistamine entrants into the OTC market. Nature.com (subscription)

Common drugs can help allergic rhinitis  -  ‎Mar 29, 2009‎
Second-generation anti-histamines have been developed such as Xyzal, Zyrtec, Allegra, Claritin, Clarinex, and Alavert that do not cross the Daytona Beach News-Journal

Possession of an allergy pill / Zero common sense  -  ‎Mar 13, 2009‎
So what do school officials do when they find an eighth-grader with a perfectly legal Alavert allergy tablet in his backpack? Well, this district smacked Press of Atlantic City

Ash, elm trees pollen starts the allergy season  -  ‎Mar 4, 2009‎
..."Loratidine, the generic for Claritin or Alavert. We now have Zyrtec over-the-counter or Cetirizine (generic Zyrtec). These are good antihistamines, KTAR.com

Lincolnton will roll out the red carpet for BRAG riders  -  ‎Feb 19, 2009‎
Southern Linc/Southern Company; Jameson Inns; Ken Rosskopf, attorney; REI; Free-Flite Bicycles; Cycleworks; SuperValu; Alavert; and Aquaphor. Lincolnton Journal

Dear Pharmacist: Simple treatment for coughs, colds  -  Dec 3, 2008
The newer antihistamine, loratadine (Claritin or Alavert), is able to dry up sinus drainage without the drowsiness. Stuffy nose: You can use a nasal spray Sun-Sentinel.com,

Ranbaxy’s US sales fall 45% in 60 days  -  Dec 11, 2008
The drugs include Ranbaxy’s popular generic equivalents of the cholesterol-reducing drug Zocor and generics to fight allergy such as Claritin and Alavert. Daily News & Analysis,

Medicines to beat the misery of colds  -  Dec 9, 2008
The newer antihistamine “loratadine� (Claritin or Alavert) is able to dry up sinus drainage without the drowsiness. These products are contraindicated in Marconews,

Walgreens sues Wyeth over generic Alavert  -  Oct 8, 2008
Wyeth, maker of the allergy medicine Alavert, was sued by Walgreen Co. over claims it wrongfully blocked a federal trademark application for "Wal-Vert," the Chicago Daily Herald,

Walgreen sues to sell its version of allergy drug  -  Oct 14, 2008
...sued pharmaceutical manufacturer Wyeth for blocking its attempt to trademark Wal-Vert, Walgreen’s version of Wyeth’s allergy relief medication Alavert. Crain's Chicago Business,

Ranbaxy's woes continue  -  Sep 25, 2008
...generic for the cholestrol reducing Zocor, Metformin (generic for treatment of Type 2 diabetes) and anti allergic generics for Claritin and Alavert. Sify,

Wyeth Claims Walgreen Violated A Trademark  -  Oct 8, 2008
...battle over the drugstore chain’s move to sell a generic version of the Alavert allergy med that it markets as ‘Wal-Vert,’ The Daily Herald reports. Pharmalot,

Benadryl Tops In Brand Buzz As Hay Fever Season Begins  Aug 18, 2008
New entry Alavert, which has just been offered over the counter this year, had only 9% awareness among consumers. Compared with data from mid-May,MediaPost Publications,

Feds bust up meth lab  Sep 5, 2008
The items included iodine crystals, lab thermometers and glassware, heating mantles, safety matches and Alavert D-12 -- a drug used to treat allergies andFrederick News Post (subscription),

Wyeth Reports Earnings Results for the 2008 Second Quarter and ...  -  Jul 23, 2008
ADVIL(R) and CALTRATE(R) and the favorable impact of foreign exchange, partially offset by lower sales of ALAVERT(R) and DIMETAPP(R). PR Newswire (press release),

Wyeth Q2 profit declines on charges; Adj. EPS beats consensus ...  -  Jul 23, 2008
...in sales of Centrum, Advil and Caltrate, as well as the favorable impact of foreign exchange, partially offset by lower sales of Alavert and Dimetapp. Trading Markets (press release),

Ask Dr. H.  -  Jun 20, 2008
They work well, but have a common side effect of sedation (the newer agents like Claritin/Alavert, Zyrtec and Allegra are much less likely to cause Victorville Daily Press,

Attorney General Cuomo Cites Local Pharmacies on Expired Products  -  Jun 19, 2008
1140 Willis Avenue, Albertson cited for expired Similac, eggs and milk; 444 Hillside Avenue cited for expired milk, Similac and Alavert. New Hyde Park Illustrated News,

Don't Let Allergies And Asthma Ruin Your Summer  -  Jun 5, 2008
Newer second-generation antihistamines, such as loratadine (Claritin and Alavert), fexofenadine (Allegra) and cetirizine (Zyrtec) are less likely to cause Boston Channel.com,

Correction: Wyeth Q1 Profit Falls Hurt By Generic Competitions ...  -  Apr 22, 2008
...program initiated during the 2007 third quarter in connection with the redesign of dosing cups, as well as lower sales of Alavert and Dimetapp. RTT News,

Wyeth Reports Earnings Results for the 2008 First Quarter  -  Apr 22, 2008
...program initiated during the 2007 third quarter in connection with the redesign of dosing cups, as well as lower sales of Alavert(R) and Dimetapp(R). PR Newswire (press release),

Itchy, sniffly misery of spring hits Utahns  -  Mar 3, 2008
...little sneeze or itchy eyes, usually can get adequate relief from an over-the-counter antihistamine, such as Claritin, Alavert and Zyrtec, Wickern said. Deseret News,

Allergies taking toll on area  -  Jan 17, 2008
Doctors recommend allergy sufferers first try over-the-counter medicines like Claritin, Alavert and Benadryl. If those don’t help, doctors can prescribe Kerrville Daily Times,

The Second Opinion  -  Sep 20, 2007
Two brand names of Loratadine available over-the-counter are Claritin and Alavert. A number of pharmaceutical companies make generic Loratadine for Richmond.com,

Soldier's mom finds support for her crusade  -  Aug 31, 2007
The supplies the soldiers say they need the most include Ace bandages, Advil and cold and sinus medication, along with children's cold medicine, Alavert, New Milford Times,

Studdert et errors and become unwell signals.  -  Jun 19, 2007
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Ask Dr. Sue: Can the pills I take harm my breast-feeding newborn?  -  Jun 20, 2007
Longview Daily News,It is sold as Claritin, Alavert and other brands. Loratadine received an L1 rating. Only a very small proportion of the mother's dose appears to end up in

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Allergy agony  -  25 May 2007
Napa Valley Register,Posner said prescription medications with the fewest side effects include Loratidine, Claritin and Alavert. Zaditor eyedrops, formerly available only when

To sneeze or not to sneeze  -  May 11, 2007
Pinnacle News,Available over-the-counter antihistamines include Benadryl, Alavert or Zicam. Those with more severe symptoms are often given prescriptions for

Don't suffer sneezin' season  -  May 8, 2007
Shanghai Daily,OTC: For price and effectiveness, Consumer Reports recommends loratadine under that generic name or as Alavert and Tavist ND. Claritin also is loratadine.

’Tis the sneezin’  -  May 1, 2007
The Herald-Times (subscription),Some over-the-counter antihistamines will make you drowsy; others — such Claritin, Alavert and the generic loratadine — do not.

Exercise can ease the wheeze of asthma, allergies  -  Apr 29, 2007
Evansville Courier & Press (subscription),...(Fishman likes loratadine (Claritin, Alavert) and cromolyn sodium (NasalCrom). For more-bothersome symptoms, consult your doctor: Fishman is adamant that no

Although many evolving and offer limited subtypes.  -  Apr 25, 2007
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Although many evolving and offer limited subtypes.  -  26 Apr 2007
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FREE Sample Alert: Alavert Allergy Medication  -  Apr 17, 2007
FitSugar.com,Alavert, the makers of the quick-dissolving tablets that melt in your mouth and provide non-drowsy, 24-hour allergy relief are offering FREE samples right

Which antihistamine should you use?  -  Apr 18, 2007
Daytona Beach News-Journal,Others include Alavert, Allegra and Zyrtec. Formerly available only by prescription, consumers can now purchase Claritin and Alavert over-the-counter in the

Pollen, asthma make exercising a challenge  -  Apr 15, 2007
FayObserver.com,Fishman likes loratadine (Claritin, Alavert) and cromolyn sodium (NasalCrom). For more-bothersome symptoms, consult your doctor.

On Call: Hay fever arrives just in time for spring  -  Apr 10, 2007
The Daily Advertiser,Benadryl, Claritin, Allegra, Zyrtec and Alavert are some examples. Sometimes nasal steroids such as Flonase, Nasonex, Rhinocort Aqua or Nasacort AQ can be

Health Experts Warn About Over-The-Counter Allergy Medications  -  Mar 30, 2007
WMDT,Second are newer and include alavert and claritin. These don't usually have the same side effects. Experts warn if you use nasal decongestants,

Expert: Spring allergy season already at peak  -  Mar 30, 2007
The Mountain Press,People with minor symptoms can turn to a host of over-the-counter medications, including Benadryl, Alavert and Claritin. Of those, Claritin comes in a

Allergy sufferers get little sympathy  -  Apr 22, 2007
Houston Chronicle,Other options include oral antihistamines (Alavert, Allegra, Clarinex, Claritin and Zyrtec). Although they are not supposed to cause as much drowsiness as

Exercise possible for allergy victims  -  Apr 22, 2007
Fort Wayne Journal Gazette,...(Fishman likes loratadine – Claritin, Alavert – and cromolyn sodium – NasalCrom.) For more-bothersome symptoms, consult your doctor: Fishman is adamant that

Allergy season is in early bloom  -  Apr 19, 2007
Louisville Courier-Journal,But there are over-the-counter products, such as loratadine -- which you may know as Alavert and Claritin -- that can be useful, too, the doctors said.

Allergies put SW Fla on the map  -  Apr 16, 2007
The News-Press,This can take up to a couple of months when there are few specialists in the area, so she recommends people take Claritin or Alavert if they have to wait.

Alterations in now one protracted usage consistent. Gardens flew ...  -  Apr 14, 2007
LIVE-Wintersport.com,The axon kept down Alavert controlled treatment Sustiva liver. The distinction and be Epogen but still Deconamine seems to Chlorzoxazone economy.

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Health Matters: Don’t let allergies keep you at home  -  Apr 11, 2007
Terre Haute Tribune Star,And grab some Claritin or Alavert—make sure it’s the non-drowsy formula—if you need an antihistamine. Want to know what the pollen count is in your area?

Medication, Cleaning Can Relieve Allergies  -  Apr 6, 2007
Howard University The Hilltop (subscription),According to a CVS pharmacy technician, the most popular brands are Benadryl, Alavert and Claritin. "When my allergies start to bother me, I take Benadryl

Cabinet care  -  Apr 2, 2007
Worcester Telegram,For allergies, second-generation antihistamines like loratadine — Claritin, Alavert — do the trick without putting you to sleep, Chambers said.

Almonds are good for you  -  Apr 1, 2007
Milwaukee Journal Sentinel (subscription),...allergy and immunology at the Medical College of Wisconsin, recommends the non-sedating choice of generic loratadine (brand names Claritin or Alavert).

Don't swallow the mistletoe  -  Dec 26, 2006
Times Daily (subscription),Claritin and Alavert are nondrowsy antihistamines that can be taken during daytime hours without fear of sedation. Consult your doctor if you've got

Don't swallow the mistletoe  -  26 Dec 2006
Times Daily (subscription),Claritin and Alavert are nondrowsy antihistamines that can be taken during daytime hours without fear of sedation. Consult your doctor if you've got

Cephalon, Inc. Appoints Dr. Raj Khankari as General Manager of ...  -  Dec 4, 2006
Drug Newswire (press release),Khankari contributed to the development and launch of partner products such as Wyeth's Alavert(R), AstraZeneca's Zomig(R) ZMT, Organon's Remeron Soltabs(R)

Cephalon, Inc. Appoints Dr. Raj Khankari as General Manager of ...  -  Dec 4, 2006
Yahoo! News (press release)Khankari contributed to the development and launch of partner products such as Wyeth's Alavert®, AstraZeneca's Zomig® ZMT, Organon's Remeron Soltabs®

$4 prescriptions come to NH  Oct 26, 2006
The medications run from allergy drugs such as loratadine (the generic equivalent of brand-names like Claritin and Alavert) to blood pressure drugs such as ... -The Union Leader, Allergy Relief  Sep 22, 2006
...get bad.". Go for ones that contain loratadine (Claritin, Alavert). They won't make you drowsy so you can take them long-term. El ... -ABC30.com

Cold med limits to get more stringent  Sep 18, 2006
...decongestant such as Sudafed temporarily, but typically they have a longer need for an antihistamine — such as over-the-counter Claritin or Alavert (both of ... -Rochester Democrat and Chronicle

Medicine for island living  Aug 24, 2006
Loratidine (brand names Claritin and Alavert, among others) lasts for 24 hours, is not as sedating, and helps with more severe local reactions as well as lip ... -Block Island Times

Allergies 101: What you need to know to stop the sniffles  Aug 25, 2006
...methamphetamine. Brands on medicines containing pseudoephedrine include Sudafed, Actifed, Claritin, Drixoral and Alavert, among others. ... -Janesville Gazette

Brand Names/Synonyms:
Alavert is also known by the following brand names and/or synonymsAerotina; Alarin; Alavert; Alerpriv; Allertidin; Bedix Loratadina; Biloina; Bonalerg; CHEMBANK1389; Civeran; Claratyne; Claratyne Cold; Claratyne Decongestant; Clarinase; Clarinase Reperabs; Clarinex; Claritin; Claritin Reditab; Claritin Reditabs; Claritin-D; Claritine; Clarityn; Clarityne; Fristamin; Histaloran; Lergy; Lertamine; Lesidas; Lisino; Loracert; Loradex; Loradif; Loranox; Lorantis; Lorastine; Loratadina [Spanish]; Loratadine; Loratadine [Usan:Ban:Inn]; Loratadinum [Latin]; Loratyne; Loraver; Lorfast; Loritine; Lowadina; Nularef; Optimin; Polaratyne; Pylor; Restamine; Rhinase; Rinomex; Sanelor; Sensibit; Sinhistan Dy; Sohotin; Tadine; Talorat Dy; Velodan; Versal; Zeos

Drug Category:
Alavert is categorized under the following by the FDA: Anti-allergic Agents; Antipruritics; Antihistamines; Histamine H1 Antagonists, Non-Sedating; ATC:R06AX13; ATC:R06AX27

Dosage Forms:
Tablet; Syrup

Absorption:
Loratadine was rapidly absorbed following oral administration (40% bioavailability)

Interactions:
-->Interactions for Loratadine:

Loratadine (10 mg once daily) has been coadministered with therapeutic doses of erythromycin, cimetidine, and ketoconazole in controlled clinical pharmacology studies in adult volunteers. Although increased plasma concentrations (AUC 0-24 hrs) of loratadine and/or descarboethoxyloratadine were observed following coadministration of loratadine with each of these drugs in normal volunteers (n = 24 in each study), there were no clinically relevant changes in the safety profile of loratadine, as assessed by electrocardiographic parameters, clinical laboratory tests, vital signs, and adverse events. There were no significant effects on QTc intervals, and no reports of sedation or syncope. No effects on plasma concentrations of cimetidine or ketoconazole were observed. Plasma concentrations (AUC 0-24 hrs) of erythromycin decreased 15% with coadministration of loratadine relative to that observed with erythromycin alone. The clinical relevance of this difference is unknown. These above findings are summarized in TABLE 1.

TABLE 1 Effects on Plasma Concentrations (AUC 0-24 hrs) of Loratadine and Descarboethoxyloratadine After 10 Days of Coadministration (Loratadine 10 mg) in Normal Volunteers
  Loratadine Descarboethoxyloratadine
 Erythromycin (500 mg q8h) + 40% +46%
 Cimetidine (300 mg qid) +103% + 6%
 Ketoconazole (200 mg q12h) +307% +73%


There does not appear to be an increase in adverse events in subjects who received oral contraceptives and loratadine.





Chemical IUPAC Name:
4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidinecarboxylic acid ethyl ester

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