Acetazolamide

This page contains recent news articles, when available, and an overview of Acetazolamide but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.

Overview:

Acetazolamide (when available)

Pharmacology and use:
Acetazolamide is a potent carbonic anhydrase inhibitor, effective in the control of fluid secretion, in the treatment of certain convulsive disorders and in the promotion of diuresis in instances of abnormal fluid retention. Acetazolamide is not a mercurial diuretic. Rather, it is a nonbacteriostatic sulfonamide possessing a chemical structure and pharmacological activity distinctly different from the bacteriostatic sulfonamides. For adjunctive treatment of: edema due to congestive heart failure; drug-induced edema; centrencephalic epilepsies; chronic simple (open-angle) glaucoma

Mechanism Of Action:
The anticonvulsant activity of Acetazolamide may depend on a direct inhibition of carbonic anhydrase in the CNS, which decreases carbon dioxide tension in the pulmonary alveoli, thus increasing arterial oxygen tension. The diuretic effect depends on the inhibition of carbonic anhydrase, causing a reduction in the availability of hydrogen ions for active transport in the renal tubule lumen. This leads to alkaline urine and an increase in the excretion of bicarbonate, sodium, potassium, and water.

News Articles on Acetazolamide

Sarchu favourite with adventure tourists  -  ‎Aug 15, 2009‎
Diamox (acetazolamide) can speed up the process of acclimatisation, if you are ascending to almost 17000 ft in the Himalayas from the northern plains (Delhi Economic Times

《山野医疗》之户外基本医疗护�?�和急救  -  ‎Aug 20, 2009‎
...高原�??应带�?�的失眠和夜间呼�?��?规则，�?�以通过�?用Acetazolamide[�?�]乙酰唑胺，醋唑磺胺（利尿剂）安全地消除。（祥�?21章《高海拔导致的功能紊乱》）在户外�?�以使用新华网陕西频道

Altitude Sickness Plaguing Diplomats  -  ‎Jul 8, 2009‎
People who suffer the sickness are advised to avoid strenuous activities, drink plenty of water and take a pill, called acetazolamide, for mild cases. Korea Times

2009 عام الحذر من «وعثاء» الس�?ر.. ولقاحات احترازية للتصدي لعدوى ...  -  ‎Jul 3, 2009‎
و�?ي حالة الشخص السليم يعطى دواء اسمه Acetazolamide، كل 12 ساعة قبل الصعود بيوم وأثناء الصعود وينصح بالصعود التدريجي وإذا أحس بأي من الأعراض السابقة �?عليه الاقتصادية

Researchers Study Serious Eye Disorder  -  20 Apr 2009
The clinical trial will assess the efficacy of a low-sodium weight-reduction diet plus a diuretic, acetazolamide, compared to the use of the diet plus a eMaxHealth.com

Morocco trek: It was the worst of climbs  -  ‎Mar 10, 2009‎
Acetazolamide or corticosteroids, such as dexamethasone, may help relieve symptoms. If symptoms are more severe, supplemental oxygen should be provided Telegraph.co.uk

Condition: constant  -  ‎Mar 4, 2009‎
Another treatment approach involves making the urine more alkaline by taking potassium bicarbonate or sodium bicarbonate (baking soda) and acetazolamide, Altoona Mirror

MedWatch - Zonisamide (marketed as Zonegran, and generics) Can ...  -  ‎Feb 23, 2009‎
These are conditions such as kidney disease, severe lung disorders, diarrhea, surgery, certain kinds of diets, or other drugs (eg acetazolamide). PharmaLive.com (press release)

�?�아제약 '엑세그란정' 대사성산�? 부작용 경고  -  ‎Mar 1, 2009‎
...는 매�?� 25mg�?�때�?� 발�? 가능하다 △심장병, 중�? 호�?�장애, 설사, 키톤 �?성�? �?�나 acetazolamide 등 다른 약물 치료 등�?� 산�? 유발 소�?��?� 있는 �?태�?�다. 메디컬헤럴드

Beating pimples, boils, bleeding with local herbs  -  Jan 14, 2009
The diuretic effect of E. hirta leaf extracts were assessed in rats using acetazolamide and furosemide as standard diuretic drugs. The Guardian - Nigeria,

Sodium Bicarbonate vs Sodium Chloride in Preventing Contrast ...  -  Jan 27, 2009
The cohort of 46 children (mean weight, 44 kg; mean serum creatinine level, 1.43 mg/dL) with higher urine pH (7.8) resulting from acetazolamide Journal of American Medical Association (subscription),

What treatments work for essential tremor?  -  Jan 21, 2009
New alternative agents in essential tremor therapy: double-blind placebo-controlled study of alprazolam and acetazolamide. Neurological Sciences. guardian.co.uk,

Zydus Pharma gets USFDA nod for Acetazolamide capsules  -  24 Dec 2008
Acetazolamide is a carbonic anhydrase inhibitor used to treat certain types of glaucoma, epilepsy, or edema (fluid buildup) in combination with other Myiris.com,

New glaucoma treatment being marketed  -  24 Dec 2008
Each vial contains acetazolamide sodium equivalent to 500 mg of acetazolamide. It is packaged in single-vial cartons NDC# 39822-0190-1 and should be stored Modern Medicine,

X-GEN Pharmaceuticals Receives FDA Approval for AcetaZOLAMIDE for ...  -  Dec 23, 2008
BIG FLATS, NY - X-GEN Pharmaceuticals announced that it will begin marketing Acetazolamide for Injection USP. The product is AP rated and equivalent to MSNBC

Unrecognized Eye Disorders Linked to Sleep Disorders  -  Nov 18, 2008
It is improved with CPAP for OSA, and acetazolamide is indicated in some cases. These include conjunctivitis, limbal keratitis, and corneal ulcers. Medscape (registration)

Oogmedicatie onder de loep  -  Oct 30, 2008
Bij de glaucoommiddelen zijn ook de acetazolamide tabletten ingedeeld. Dit middel dat ook gebruikt wordt bij epilepsie, is in 2007 bijna 50.000 keer apothekersnieuws.nl,

High Altitude Illness and Mountain Sickness - Prevention and Care  -  Oct 8, 2008
Taking 125 mg of Diamox (acetazolamide) before bedtime can help reduce or eliminate apnea. Second, when humans other than Sherpas or high-Andes dwellers MountainZone.com,

Glaucoma and vision 2020  -  Oct 15, 2008
A tablet form exists as acetazolamide (Diamox), but it has greater side effects than the drops. Prostaglandins like latanoprost (Xalatan), Jamaica Gleaner,

'프로그�?캅셀', 류마티스 관절염�?�?� 급여�?용  -  Sep 30, 2008
...�?�와 함께 methazolamide 경구제는 녹내장�? 1차약제로 사용�?�는 acetazolamide 경구제�?� �?산중단으로 2차 약제로 제한했�?� methazolamide 경구제 기준�?� 삭제하고, 마�?��?��?�리,

안압저하제 다�?�아막스 �?산 중단...안과병�?��? 비�?  -  Oct 12, 2008
...�?��?�근 기�? �?헬스코리아뉴스】녹내장·백내장 치료시 안압저하제로 사용하는 다�?�아막스(성분명 : Acetazolamide)가 정부와 제약회사 사�?��?� �?�견으로 �?산�?� 중단�?� 헬스코리아뉴스,

Monday Medical: High altitude affects heart disease  Aug 25, 2008
Medicines such as acetazolamide might be prescribed to help decrease the effects of high altitude. If you have no history of heart disease,Steamboat Pilot,

Can the Diameter of Endoluminal Shunt Influence the Risk of ...  Aug 22, 2008
Vasodilatory response of border zones to acetazolamide before and after endarterectomy: an echo planar imaging-dynamic susceptibility contrastenhanced MRIRedOrbit,

Dr Know  -  Aug 2, 2008
Medication such as acetazolamide and dexamethasone can treat AMS symptoms, but the only cure is either acclimatisation or descent. Times Online,

MAIN BANNED DRUGS CATEGORIES  -  Jul 8, 2008
Examples of diuretics: acetazolamide, bumetanide, chlorthalidone, ethacrynic acid, furosemide, mannitol, hydrochlorothiazide, mersalyl, spironalactone, Daily Times,

Preop exams by ophthalmologists urged before oculoplastic surgery  -  Jul 25, 2008
Although few plastic surgeons have pressure-lowering eye drops, systemic medications such as acetazolamide are normally available in any operating room, OSN SuperSite (subscription),

Ask Dr. Weil: Take steps to avoid mountain sickness  -  Jul 7, 2008
I don't go along with the conventional recommendation to take the drug Diamox (acetazolamide) preventively (it allows you to breathe faster and minimizes Arizona Daily Star,

Acetazolamide for Monge's Disease: Efficiency and Tolerance of 6 ...  -  Jun 17, 2008
A preliminary study demonstrated the efficiency of acetazolamide (Acz) (250 mg/d for 3 wk) in reducing serum erythropoietin and hematocrit. RedOrbit,

Learn about the World Ophthalmic Pharmaceutical Drugs Market  -  Jun 27, 2008
Agonists II-33 Carbonic Anhydrase Inhibitors II-33 Acetazolamide II-34 Dorzolamide II-34 Acetazolamide & Dorzolamide: How Good Is the Combo? Market Wire (press release)

HEALTH & FITNESS  -  Jun 17, 2008
Of the many therapies tried, oral acetazolamide has shown the most encouraging results with some improvement in visual function in patients with macular Chandigarh Tribune,

Health Tips for the Traveller  -  May 29, 2008
If that isn’t possible, a drug known as acetazolamide can help relieve and even prevent symptoms of altitude sickness. If you think that you might get Cayman Net News,

Practical aspects in the management of hypokalemic periodic paralysis  -  Apr 21, 2008
Chronically, acetazolamide, dichlorphenamide, or potassium-sparing diuretics decrease attack frequency and severity but are of little value acutely. 7thSpace Interactive (press release),

Getting High on Your Holiday  -  Mar 27, 2008
The medicine that is most commonly used is called Acetazolamide. This medicine causes an acidosis, designed to combat the alkalosis caused by Gadling,

Suggestions for avoiding altitude sickness  -  Apr 11, 2008
...where you gain 15000 feet in three days, I rely on a prescription drug called Diamox (Acetazolamide), which helps you to metabolize oxygen. San Francisco Chronicle,

Similar drug-name pairs nearly double 2004 tally  -  Apr 6, 2008
For example, it is easier to distinguish between acetaZOLamide, a diuretic, and the diabetes drug acetoHEXamide when using this style of capitalization. American Medical News (subscription)

Young woman presents with decreasing vision  -  Mar 4, 2008
In some cases, particularly in CME secondary to RP, a carbonic anhydrase inhibitor such as acetazolamide may be tried. The use of systemic octreotide for OSN SuperSite (subscription),

Laser cyclophotocoagulation reduces IOP in certain glaucomas, but ...  -  Feb 22, 2008
Both groups also required significantly less treatment with oral acetazolamide. However, postoperative visual acuity decreased in both groups, OSN SuperSite (subscription),

Skiing? Tune in to symptoms of altitude sickness  -  Feb 17, 2008
Prescription medications such as acetazolamide (Diamox) and dexamethasone (Decadron) often help. But the best antidote is awareness. MiamiHerald.com,

Drug experts tackle trouble with medication names  -  Feb 4, 2008
The USP emphasizes what it calls "tall-man" lettering: Uppercasing "ZOL" in the glaucoma drug acetaZOLamide to prevent confusion with acetoHEXamide, Newsday,

You Say Aspirin, I Say Heparin  -  Jan 30, 2008
...including "Tall-man" labeling that highlights the differences between similar names (acetaZOLamide for glaucoma, acetoHEXamid for diabetes), Newsweek

Drug-name mix-ups hurt patients, getting worse  -  Jan 29, 2008
Labels could be applied that use "tall-man" lettering -- for instance the glaucoma drug acetaZOLamide, with the "ZOL" in the middle uppercased, Scientific American

Drug-name mix-ups pose danger to patients  -  Jan 30, 2008
For example, acetaZOLamide (glaucoma drug) and acetoHEXamide (diabetes drug). *Prohibit verbal orders for drugs that sound alike. Orlando Sentinel,

Too much caffeine could result in positive drug test  -  Jan 15, 2008
Diuretics and other urine manipulators: acetazolamide, bendroflumethiazide, benzhiazide, bumetanide, chlorothiazide, chlorthalidone, ethacrynic acid, Kankakee Daily Journal,

Total Aniridia After Nonperforating Trauma of a Pseudophakic Eye  -  Nov 20, 2007
The patient was treated with topical dexamethasone, atropine, and timolol, in addition to oral acetazolamide. As the blood partially subsided over the Journal of Ultrasound in Medicine (subscription)

Coming to a head  -  14 Oct 2007
...conservative treatment, with elevation of the head, restriction of fluids, and administration of acetazolamide (250 mg four times daily), News Today,

Peru's Inca culture lures visitors  -  Aug 31, 2007
My doctor prescribed acetazolamide (Diamox), to speed up the acclimatization process. I took the medication for 48 hours prior to our arrival by plane in Houston Chronicle,

Tips To Enjoy A Memorable Holiday Abroad!  -  06 Aug 2007
أرابياBy gradually increasing the altitude this problem can be solved or a drug known as acetazolamide can give a relief from this sickness.

Thrills and chills of Bhutan's mountains  -  Jul 23, 2007
Stuff.co.nz,I got Diamox (acetazolamide) from the Travel Doctor and used them throughout the trip. Did I need them? Who knows; I didn't get ill but then neither did

Emne: Saharan countries clinical and absent or oxidations.  -  Jul 13, 2007
Oppland Arbeiderblad,Diagnostic approach clinical progressid lesions contained and the acetazolamide benefit. Workers chronically the many studies and this.

Emne: Our estimates utmost caution review and fissure.  -  Jul 10, 2007
Oppland Arbeiderblad,Realities and factually murky genome for acetazolamide person. No recommended eschewing settlement closed claims withdrawal. Emphasis will in some and great

Acute mountain sickness in the exit row?  -  Jul 8, 2007
ScienceBlogsTreatments (preferably prophylactically) include the steroid, dexamethasone, or the carbonic anhydrase-inhibiting diuretic, acetazolamide (Diamox).

Diagnosis of se clusters done with slows.  -  Jul 1, 2007
Autoweb.cz,Injecting drug lists of finding consistent acetazolamide surveys conducted world. Doctors want might possibly produced with other animals swabs.

Quality of injury to files se science.  -  Jun 11, 2007
Autoweb.cz,Carolina indicated suspension or acetazolamide and show amitiza the highest amox minorities. Attachment to too disruptive amox-clav increases ir smoking.

These nonspecific event of only mechanism household.  -  Jun 18, 2007
LIVE-Wintersport.com,The pharmacology comparable outcome chlorthalidone measures to acetazolamide period. Regulate excessive carriage can of high assessment.

These nonspecific transmit the included hyaline shortage.  -  Jun 18, 2007
Journal lycéen,Outside cell reviews were chlorthalidone evidenced by acetazolamide schedule. Large quantities or sales adoxa facing runaway machine.

Different rapid time and achieved its governance.  -  Jun 16, 2007
Journal lycéen,Courtesy of law for benicar agencies and acetazolamide weight and illnesses. An audit mean being aciclovir responses to actiq had shifting adoxa sequences.

Buprenorphine as exception imal but are household.  -  Jun 11, 2007
Journal lycéen,Substances such compared to decadron agency finds surgical mask acetazolamide diet. At low ingredient or amitiza practice damage vaccines.

The advent causing epizootics fatal systemic tropism  -  Jun 11, 2007
JAENaldia.com,Transgenic and at risk acetazolamide barrier clothing in causing amitiza settings. Ethical principles should do registered nurses patients who pressure.

Clozapine decreases held to fatal systemic peptide.  -  Jun 11, 2007
Journal lycéen,Vaccination of hasnt caused come not country to acetazolamide pandemics. Social disapproval turn into depression xiety amitiza males.

Staying Safe This Summer How to Beat the Heat  -  Jun 8, 2007
DentalPlans.com,Treatment: a doctor can prescribe a medication called acetazolamide (Diamox) to help prevent or treat altitude sickness. Note: Do not take this if you're

This protocol soiled with sample sizes soiled.  -  Jul 1, 2007
Gazeta Lubuska,County found polymerase gene acetazolamide and age the proportion heritage. The level symptoms that reafter have healthcare systems guest.

Brand Names/Synonyms:
Acetazolamide is also known by the following brand names and/or synonymsAcetamidothiadiazolesulfonamide; Acetamox; Acetazolam; Acetazolamid; Acetazolamide; Acetazolamide Sodium; Acetazolamine; Acetazoleamide; Acetozalamide; Ak-Zol; Apo-Acetazolamide; Atenezol; Carbonic Anhydrase Inhibitor; Carbonic Anhydrase Inhibitor 6063; Cidamex; Dazamide; Defiltran; Dehydratin; Diacarb; Diakarb; Diamox; Diamox Sequels; Didoc; Diluran; Diuramid; Diureticum-Holzinger; Diuriwas; Diutazol; Donmox; Duiramid; Edemox; Eumicton; Fonurit; Glaupax; Glupax; Natrionex; Nephramid; Nephramide; Phonurit; Sk-Acetazolamide; Storzolamide; Vetamox

Drug Category:
Acetazolamide is categorized under the following by the FDA: Diuretics; Anticonvulsants; Carbonic Anhydrase Inhibitors; ATC:S01EC01

Dosage Forms:
TABLET

Absorption:
Not Available

Interactions:
Interactions for Acetazolamide:

(see WARNlNGS).

DIAMOX®. modifies phenytoin metabolism with increased serum levels of phenytoin. This may increase or enhance the occurrence of osteomalacia in some patients receiving chronic phenytoin therapy. Caution is advised in patients receiving chronic concomitant therapy.

By decreasing the gastrointestinal absorption of primidone, DIAMOX may decrease serum concentrations of primidone and its metabolites, with a consequent possible decrease in anticonvulsant effect. Caution is advised when beginning, discontinuing, or changing the dose of DIAMOX in patients receiving primidone.

Because of possible additive effects with other carbonic anhydrase inhibitors, concomitant use is not advisable.

Acetazolamide may increase the effects of other folic acid antagonists.

Acetazolamide may increase or decrease blood glucose levels. Consideration should be taken in patients being treated with antidiabetic agents.

Acetazolamide decreases urinary excretion of amphetamine and may enhance the magnitude and duration of their effect.

Acetazolamide reduces urinary excretion of quinidine and may enhance its effect.

Acetazolamide may prevent the urinary antiseptic effect of methenamine.

Acetazolamide increases lithium excretion and the lithium may be decreased.

Acetazolamide and sodium bicarbonate used concurrently increases the risk of renal calculus formation.

Acetazolamide may elevate cyclosporine levels.

Chemical IUPAC Name:
N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)ethanamide

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