Acetaminophen

This page contains recent news articles, when available, and an overview of Acetaminophen but does not offer medical advice. You should contact your physician with regard to any health issues or concerns.


Overview:

Acetaminophen
(when available)

Pharmacology and use:
Caffeine, a naturally occurring xanthine derivative like theobromine and the bronchodilator theophylline, is used as a CNS stimulant, mild diuretic, and respiratory stimulant (in neonates with apnea of prematurity). Often combined with analgesics or with ergot alkaloids, caffeine is used to treat migraine and other headache types. Over the counter, caffeine is available to treat drowsiness or mild water-weight gain. For management of fatigue, orthostatic hypotension, and for the short term treatment of apnea of prematurity in infants.

Mechanism Of Action:
Caffeine stimulates medullary, vagal, vasomotor, and respiratory centers, promoting bradycardia, vasoconstriction, and increased respiratory rate. This action was previously believed to be due primarily to increased intracellular cyclic 3′,5′-adenosine monophosphate (cyclic AMP) following inhibition of phosphodiesterase, the enzyme that degrades cyclic AMP. It is now thought that xanthines such as caffeine act as agonists at adenosine-receptors within the plasma membrane of virtually every cell. As adenosine acts as an autocoid, inhibiting the release of neurotransmitters from presynaptic sites but augmenting the actions of norepinephrine or angiotensin, antagonism of adenosine receptors promotes neurotransmitter release. This explains the stimulatory effects of caffeine. Blockade of the adenosine A1 receptor in the heart leads to the accelerated, pronounced "pounding" of the heart upon caffeine intake.

News Articles on Caffeine

Eco-friendly meds? Fashionable and funny, too  -  30 Aug 2009
For example, the headache package reads: “These pills contain 500mg acetaminophen. They don't contain Red Dye #40. If you enjoy Red Dye #40, you will have Grand Forks Herald

NSAIDS a deadly health risk  -  30 Aug 2009
NSAIDS, also known as over-the-counter pain relievers such as aspirin, ibuprofen and acetaminophen, are responsible for almost as many deaths as AIDS. Examiner.com

BioElectronics Announces Completion of Clinical Study -- Preparing ...  -  30 Aug 2009
As a physician I am always concerned about the overuse of acetaminophen, narcotics and NSAIDs. Whenever possible our role is to reduce the use of these PR-USA.net (press release)

For a broken arm, give a child ibuprofen -- not codeine ...  -  ‎Aug 18, 2009‎
Not only did the ibuprofen work just fine in controlling pain -- at least as good as the codeine-laced acetaminophen -- the medicine normally associated Los Angeles Times

Some patients concerned over new recommendations for acetaminophen use  -  ‎Aug 24, 2009‎
Brandon Johnson takes acetaminophen for headaches. When he had his wisdom teeth removed, and burst a blood vessel in his eye, his doctor prescribed Vicodin, StandardNet

Using Acetaminophen  -  ‎Aug 26, 2009‎
...(NAPSI)-Acetaminophen, an active ingredient found in many pain relievers, is safe and effective when taken as directed. According to the US Food and Drug North American Press Syndicate

Cumberland Pharma Q2 Profit Declines - Update  -  ‎Aug 27, 2009‎
Acetadote is an approved injectable product in the United States for the treatment of acetaminophen overdose, one of the major cause of poisonings RTT News

Federal Circuit Vacates Ultracet Obviousness Decision  -  ‎Aug 26, 2009‎
Ultracet is the brand name for Ortho's combination pill of the popular drug acetaminophen with light opioid tramadol. The current patent rights are found in Patently-O

Ibuprofen Effective for Outpatient Analgesia in Children With Arm ...  -  ‎Aug 25, 2009‎
August 25, 2009 — Ibuprofen is at least as effective as acetaminophen with codeine for outpatient analgesia for children with arm fractures, according to Medscape

Health Tip: Preventing a Peptic Ulcer  -  ‎Aug 28, 2009‎
...avoid anti-inflammatory drugs (NSAIDs) such as naproxen, ibuprofen or aspirin. Consider, with your doctor's approval, acetaminophen instead. U.S. News & World Report

Urine testing for drug compatibility  -  ‎Aug 28, 2009‎
Urine specimens were collected before and six hours after a dose of the common painkiller acetaminophen, widely known as paracetamol in the UK. Examiner.com

Vicodin, Tylenol among drugs FDA scrutinizing  -  ‎Aug 14, 2009‎
In the minds of many consumers, acetaminophen has long been the safest of pain relievers. Best known by the name brand Tylenol, it was first marketed in the San Francisco Chronicle

Flexcin Arthritis Remedy Proves Worthy Substitution for Acetaminophen  -  ‎Aug 26, 2009‎
FORT MYERS, FL -- 08/26/09 -- An advisory panel for the Food and Drug Administration (FDA) recently recommended limiting sales of acetaminophen products Earthtimes (press release)

Acetaminophen-containing products: safety, overdose prevention ...  -  ‎Aug 24, 2009‎
Many over-the-counter (OTC) and prescription drug products contain different combinations and concentrations of acetaminophen, posing the potential for AAP News (subscription)

Ibuprofen best for kids with broken arms  -  ‎Aug 28, 2009‎
Researchers randomly assigned 336 children between the ages of 4 to 18 to go with liquid versions of either ibuprofen or the acetaminophen-codeine Examiner.com

Healthy Living: Pain reliever acetaminophen is safe when used properly  -  ‎Aug 10, 2009‎
Acetaminophen, more commonly known as the brand name, Tylenol, and by its chemical abbreviation, APAP, is the most widely used medication Norwich Bulletin

A Nurse Reviews 'Nurse Jackie'  -  ‎Aug 5, 2009‎
Percocet is a combination of the painkiller oxycodone and acetaminophen, the ingredient in Tylenol. Acetaminophen has the potential to cause liver failure New York Times

Urine Test May Predict Drug Responses  -  ‎Aug 10, 2009‎
A simple urine sample can be used to tell how people will respond to the common analgesic acetaminophen, researchers said, and the same idea might one day MedPage Today

Today's Health Tip: Don't overdo it with acetaminophen  -  ‎Aug 7, 2009‎
Acetaminophen is an active ingredient in many over-the-counter and prescription medicines used to relieve pain or reduce a fever. According to the Food and Ithaca Journal

University prepares for H1N1 virus  -  ‎Aug 27, 2009‎
Treat symptoms of fever and body aches with acetaminophen or ibuprofen. * Throat lozenges and decongestants may be useful for sore throat and congestion. RU Daily Targum

UNCC issues advisory to keep H1N1 woes low around campus  -  ‎Aug 27, 2009‎
Parents can send flu kit care packages, including acetaminophen, a digital thermometer, hand sanitizer, disinfectant wipes, Gatorade drink mix packets and News14.com

Two Health-Care IPOs Coming This Week  -  ‎Aug 10, 2009‎
The latter is interesting because the FDA recently stepped up its warning of acetaminophen overdose, notes Morningstar IPO Research. Wall Street Journal Blogs

Give Kids Ibuprofen, Not Codeine, for Broken Arms  -  ‎Aug 22, 2009‎
A study conducted at the Medical College of Wisconsin shows that the ibuprofen is superior to acetaminophen and codeine when used to treat broken arm pain. Citizens Report

NeurogesX Reports Second Quarter 2009 Results  -  ‎Aug 7, 2009‎
NeurogesX is also seeking business development partners to advance its acetaminophen and opioid prodrug product candidates. NGX-9674 and NGX-5752, PR Newswire (press release)

Docs cringe at the thought of painkillers taken off the market  -  ‎Aug 19, 2009‎
Even more than concerns about addiction, experts question the effect of opiod/acetaminophen compounds – commonly found in painkillers – on the liver. Medill Reports: Washington

70000 US kids overdose each year — accidentally — on everyday ...  -  ‎Aug 14, 2009‎
The leading culprit, which sends an estimated 7226 US kids to hospital each year: acetaminophen, or Tylenol. Acetaminophen is one of the most common TIME

What's Going Around - August 25, 2009  -  ‎Aug 25, 2009‎
Take Acetaminophen or Ibuprofen to help with your fever, if it's the flu. And avoid alcohol and tobacco. Once again, Dr. Voth says the single best way to KKTV 11 News

Over-the-Counter Painkillers... Or Plain Killers?  -  ‎Aug 7, 2009‎
This time the drug in the spotlight is acetaminophen, the over-the-counter painkiller that is the principle ingredient in Tylenol and Excedrin. Stop Aging Now

Man Accused of Filling Dead Father's Prescription  -  ‎Aug 25, 2009‎
Brewer's father passed away at the beginning of the month and the next day, Brewer filled his prescription for 90 pills of hydrocodone and acetaminophen. WDTV

Accidental deaths in Minnesota soar as more people abuse or aren't ...  -  ‎Aug 17, 2009‎
It wasn't until just before Nelson's death on March 18, 2007, that a toxicology report revealed the culprit: acetaminophen, the active ingredient in Tylenol Pioneer Press

The 404 414: Where we eat Snow Leopard for dinner  -  ‎Aug 28, 2009‎
...(eg Tylenol over plain Acetaminophen). by Cruton502 August 28, 2009 11:55 AM PDT The people of Walmart blog is broken! Do you think its to busy or did CNET News

FDA Concern Highlights Even The Most Common Drugs Are Still  -  ‎Aug 19, 2009‎
In recent months the FDA has been proposing a ban or restrictions on use of acetaminophen, the ingredient found in popular over-the-counter products like TransWorldNews (press release)

Survey helps discern characteristics of pediatric medication use  -  ‎Aug 18, 2009‎
Acetaminophen, ibuprofen and multivitamins were at the top of the list, with over-the-counter formulations outnumbering prescription usage two-to-one among Pediatric SuperSite

Paracetamol 'raises asthma risk'  -  ‎Aug 27, 2009‎
There was also a 28% increase in the risk of asthma and wheezing in babies born to women who used acetaminophen while pregnant. Pulse

Law and Order  -  ‎Aug 21, 2009‎
These include 35 syringes of Dilauded (hydromophone), five tablets of Lortab (hydromorphone and acetaminophen) and two tablets of Percocet (oxycodone and Gary Post Tribune

Drug Reponses Could be Predicted by Urine Testing  -  ‎Aug 19, 2009‎
A standard urine screen can verify how a patient will react to acetaminophen, according to researchers, and it could be the first step toward predicting TestCountry.com

Drug competition in peril  -  ‎Aug 28, 2009‎
Given that poor countries are dependent on generics even for inexpensive medications like ibuprofen and acetaminophen, flawed biosimilars legislation would Baltimore Sun

J&J Wins Appeal Reviving Patent on Ultracet Drug  -  ‎Aug 26, 2009‎
Ultracet combines acetaminophen, the main ingredient in Johnson & Johnson's Tylenol, with tramadol hydrochloride, a compound used in the painkiller Ultram. Bloomberg

How to treat a wasp sting:  -  ‎Aug 26, 2009‎
Take an antihistamine such as Benadryl for itching, and take ibuprofen or acetaminophen for pain relief. • Wash the sting site with soap and water. Barrie Advance

www.standoutstocks.com: Stocks That Standout For 8/20/2009 Are ...  -  ‎Aug 20, 2009‎
Current treatments for chronic pain include both opiate-based analgesics including Vicodin, Percocet, and Morphine, and those containing acetaminophen, Trading Markets (press release)

Pain relief options for kids  -  ‎Aug 19, 2009‎
And the recent news that high doses of acetaminophen can lead to liver damage is adding to the confusion over the popular over-the-counter pain relievers. Hartford Courant

Researchers recommend ibuprofen for treating fracture pain in children  -  ‎Aug 19, 2009‎
Researchers found that ibuprofen works as well as acetaminophen with codeine in relieving pain in children with a broken arm. No overall difference was SmartBrief

17-Year-Old Girl Arrested For Drugs At Coosa High School  -  ‎Aug 13, 2009‎
Police say McCollum had five tablets of Midrin, a prescription headache medication that contains isometheptene, acetaminophen and dichloralphenazone, Rome News Wire

Trendy treatments to help you battle the common cold  -  ‎Aug 7, 2009‎
Acetaminophen can cause liver damage when taken in large doses. Aspirin, too, has the potential to cause harm to the kidneys and liver; it has acquired a Examiner.com

Help Remedies Overhauls OTC, Pushes for Better Health Care  -  ‎Aug 9, 2009‎
The packages are white, embellished only with the does-what-it-says product name and a clear description of the contents, such as "16 acetaminophen caplets AdAge.com (subscription)

First Defense Nasal Screen Comp. Releases New Protection Product ...  -  ‎Aug 29, 2009‎
Take acetaminophen, such as Tylenol, for muscle aches and pain, but not for a low grade fever. It is helping to fight the virus." Prevention is the key, PR Web (press release)

Cold Medicine Drug Abuse  -  ‎Aug 4, 2009‎
Acetaminophen has been established to cause liver damage in high doses. Before the US Food and Drug Administration (FDA) replaced the narcotic codeine with TransWorldNews (press release)

Brand Names/Synonyms:
Acetaminophen is also known by the following brand names and/or synonyms4'-Hydroxyacetanilide; 4'-Hydroxyacetanilide, Paracetamol; APAP; Abenol; Abensanil; Acamol; Accu-Tap; Acephen; Aceta; Aceta Elixir; Aceta Tablets; Acetagesic; Acetalgin; Acetaminofen; Acetaminophen; Acetaminophen Uniserts; Actamin; Actamin Extra; Actamin Super; Actimol Chewable Tablets; Actimol Children's Suspension; Actimol Infants' Suspension; Actimol Junior Strength Caplets; Algotropyl; Allay; Alpiny; Alpinyl; Alvedon; Amacodone; Amadil; Aminofen; Aminofen Max; Anacin; Anacin-3; Anacin-3 Extra Strength; Anaflon; Anapap; Anelix; Anexsia; Anexsia 10/660; Anexsia 5/325; Anexsia 7.5/325; Anexsia 7.5/650; Anhiba; Anoquan; Apacet; Apacet Capsules; Apacet Elixir; Apacet Extra Strength Caplets; Apacet Extra Strength Tablets; Apacet Regular Strength Tablets; Apadon; Apamid; Apamide; Apo-Acetaminophen; Arthritis Pain Formula; Aspirin Free Anacin Maximum Strength Caplets; Aspirin Free Anacin Maximum Strength Gel Caplets; Aspirin Free Anacin Maximum Strength Tablets; Aspirin-Free Excedrin Caplets; Atasol Caplets; Atasol Drops; Atasol Forte Caplets; Atasol Forte Tablets; Atasol Oral Solution; Atasol Tablets; Bancap; Bancap Hc; Banesin; Bayer Select Maximum Strength Headache Pain Relief Formula; Bickie-Mol; Bromo Seltzer; Bucet; Butalbital; Butapap; Calpol; Captin; Cetadol; Clixodyne; Co-Gesic; Conacetol; Dafalgan; Dapa; Dapa X-S; Darvocet; Darvocet-N 100; Darvocet-N 50; Datril; Datril Extra-Strength; Dhc Plus; Dimindol; Dirox; Disprol; Dolene Ap-65; Doliprane; Dolprone; Drixoral Plus; Dularin; Duradyne Dhc; Dymadon; Dypap; Elixodyne; Enelfa; Eneril; Esgic; Esgic-Plus; Eu-Med; Excedrin Caplets; Excedrin Extra Strength Caplets; Exdol; Exdol Strong; Febridol; Febrilix; Febrinol; Febro-Gesic; Febrolin; Femcet; Fendon; Feverall; Feverall Junior Strength; Feverall Sprinkle Caps Junior Strength; Fevor; Finimal; Fioricet; Free; G 1; G-1; Gelocatil; Genapap; Genapap Children's Elixir; Genapap Children's Tablets; Genapap Extra Strength Caplets; Genapap Extra Strength Tablets; Genapap Regular Strength Tablets; Genebs; Genebs Extra Strength Caplets; Genebs Regular Strength Tablets; Genebs X-Tra; Hedex; Homoolan; Hy-Phen; Hydrocet; Infants' Feverall; Injectapap; Janupap; Korum; Lestemp; Liquagesic; Liquiprin; Liquiprin Children's Elixir; Liquiprin Infants" Drops; Lonarid; Lorcet-Hd; Lortab; Lyteca; Lyteca Syrup; Meda; Medigesic Plus; Momentum; Multin; Myapap; NAPA; Napafen; Napap; Naprinol; Nealgyl; Nebs; Neopap; Neotrend; Nobedon; Norcet; Norco; O-Acetaminophenol; Oraphen; Oraphen-Pd; Ortensan; Oxycet; Oxycodone 2.5/Apap 500; Oxycodone 5/Apap 500; P-Acetamidophenol; P-Acetaminophenol; P-Hydroxyacetanilide; P-Hydroxyphenolacetamide; Pacemo; Painex; Paldesic; Panadol; Panadol Extra Strength; Panadol Junior Strength Caplets; Panadol Maximum Strength Caplets; Panadol Maximum Strength Tablets; Panaleve; Panasorb; Panets; Panex; Panofen; Papa-Deine #3; Papa-Deine #4; Paracet; Paracetamol; Paracetamol Dc; Paracetamol Ph Eur; Paracetamole; Paracetamolo; Paracetanol; Parapan; Paraspen; Parelan; Parmol; Pasolind; Pasolind N; Pedric; Percocet; Phenaphen; Phenaphen Caplets; Phendon; Phrenilin; Phrenilin Forte; Prompt; Propacet 100; Proval #3; Pyrinazine; Redutemp; Rivalgyl; Robigesic; Rounox; Roxicet; Roxicet 5/500; Roxilox; Salzone; Sedapap; Servigesic; Sk-Apap; Snaplets-Fr; St. Joseph; St. Joseph Fever Reducer; Suppap; Suppap-120; Suppap-325; Suppap-650; Tabalgin; Talacen; Tapanol; Tapanol Extra Strength Caplets; Tapanol Extra Strength Tablets; Tapar; Tavist Allergy/Sinus/Headache; Temlo; Tempanal; Tempra; Tempra Caplets; Tempra Chewable Tablets; Tempra D.S; Tempra Drops; Tempra Syrup; Tencon; Tibinide; Tibizide; Tisin; Tisiodrazida; Tizide; Tralgon; Triad; Triaprin; Tussapap; Tycolet; Tylenol; Tylenol Arthritis Extended Relief; Tylenol Caplets; Tylenol Children's Chewable Tablets; Tylenol Children's Elixir; Tylenol Drops; Tylenol Elixir; Tylenol Extra Strength Adult Liquid Pain Reliever; Tylenol Extra Strength Caplets; Tylenol Extra Strength Gelcaps; Tylenol Extra Strength Tablets; Tylenol Gelcaps; Tylenol Infants Drops; Tylenol Infants" Suspension Drops; Tylenol Junior Strength Caplets; Tylenol Junior Strength Chewable Tablets; Tylenol Regular Strength Caplets; Tylenol Regular Strength Tablets; Tylenol Tablets; Tylox; Tylox-325; Ultracet; Uniserts; Valadol; Valgesic; Valorin; Valorin Extra; Vicodin; Vicodin Es; Vicodin Hp; Wygesic

Drug Category:
Acetaminophen is categorized under the following by the FDA: Analgesics; Antipyretics; ATC:N02BE01

Dosage Forms:
80 mg per mL (OTC) Atasol Drops Panadol Tempra Drops alcohol 10% Tylenol Drops [Generic] 80 mg per 5 mL (OTC) Atasol Oral Solution Panadol sodium Robigesic alcohol 8.5% Tempra Syrup 160 mg per 5 mL (OTC) Tempra Syrup Tylenol Elixir [Generic]

Absorption:
Oral _ Rapid and almost complete

Interactions:
Interactions for Acetaminophen:

No information provided.





Chemical IUPAC Name:
N-(4-hydroxyphenyl)ethanamide

:
 
Web health.mongabay.com/health


Health Home | Conditions | Cancer | Medications | Surgery | Vaccines

mongabay.com


Disclaimer:

Contact a physician with regard to health concerns. Email requests for further health information will be discarded.

The materials contained on this Web site are for informational purposes only and do not constitute health or medical advice. Use of information on this site does not create or constitute any kind of agreement or contract between you and the owners or users of this site, the owners of the servers upon which it is housed, or anyone else who is in any way connected with this site.

Many links on health.mongabay.com/health lead to other sites. health.mongabay.com/health does not sponsor, endorse or otherwise approve of the materials appearing in such sites. Nor is health.mongabay.com/health responsible for dead or misdirected links.

IF YOU NEED A LINK/TEXT REMOVED FROM THIS PAGE, PLEASE CONTACT: mongabay (at) gmail.com


COPYRIGHT 2007 MONGABAY.COM